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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIL2 All Species: 25.45
Human Site: T146 Identified Species: 56
UniProt: Q13356 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13356 NP_680481.1 520 58823 T146 K N F R D L L T D E P F S R Q
Chimpanzee Pan troglodytes XP_001168978 520 58777 T146 K N F R D L L T D E P F S R Q
Rhesus Macaque Macaca mulatta XP_001088432 378 42947 R13 P R S P R G P R L R R R Q L R
Dog Lupus familis XP_534768 523 59161 T146 K N F R D L L T D E P F S R Q
Cat Felis silvestris
Mouse Mus musculus Q9D787 521 59046 T146 K N L R D L L T D E P F S R Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079584 521 59210 T146 K S Y K D L L T D E P F T R Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611113 517 58940 D149 K N W K D L V D D T P F Q R K
Honey Bee Apis mellifera XP_623363 521 59810 N150 R N W K D L I N D Q P F T R K
Nematode Worm Caenorhab. elegans P52012 523 58515 T149 N H L K D L L T D V P F T R A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJX0 595 65005 T146 K N W K E L L T E E P F T R A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RXA6 597 65782 D162 K M W R D L V D D E E F G R R
Conservation
Percent
Protein Identity: 100 99.8 66.9 92.3 N.A. 90.2 N.A. N.A. N.A. N.A. 77.7 N.A. N.A. 54 57 48.7 N.A.
Protein Similarity: 100 100 68.4 96.5 N.A. 95.9 N.A. N.A. N.A. N.A. 88.8 N.A. N.A. 73.4 72.9 65.3 N.A.
P-Site Identity: 100 100 0 100 N.A. 93.3 N.A. N.A. N.A. N.A. 73.3 N.A. N.A. 53.3 46.6 53.3 N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 93.3 N.A. N.A. N.A. N.A. 100 N.A. N.A. 80 93.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 43.7 N.A. 39.7
Protein Similarity: N.A. N.A. N.A. 59.5 N.A. 55.6
P-Site Identity: N.A. N.A. N.A. 60 N.A. 53.3
P-Site Similarity: N.A. N.A. N.A. 93.3 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 82 0 0 19 82 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 10 64 10 0 0 0 0 % E
% Phe: 0 0 28 0 0 0 0 0 0 0 0 91 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 73 0 0 46 0 0 0 0 0 0 0 0 0 0 19 % K
% Leu: 0 0 19 0 0 91 64 0 10 0 0 0 0 10 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 64 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 10 0 0 10 0 0 0 82 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 19 0 46 % Q
% Arg: 10 10 0 46 10 0 0 10 0 10 10 10 0 91 19 % R
% Ser: 0 10 10 0 0 0 0 0 0 0 0 0 37 0 0 % S
% Thr: 0 0 0 0 0 0 0 64 0 10 0 0 37 0 0 % T
% Val: 0 0 0 0 0 0 19 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _