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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5C
All Species:
23.03
Human Site:
Y446
Identified Species:
42.22
UniProt:
Q13362
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13362
NP_002710.2
524
61061
Y446
A
N
P
Q
Y
T
V
Y
S
Q
A
S
T
M
S
Chimpanzee
Pan troglodytes
XP_510170
605
69813
K533
D
D
C
T
Q
Q
F
K
A
E
K
L
K
E
K
Rhesus Macaque
Macaca mulatta
XP_001112240
806
91497
Y728
A
N
P
Q
Y
T
V
Y
S
Q
A
S
T
V
S
Dog
Lupus familis
XP_854560
524
61058
Y446
A
N
P
Q
Y
A
V
Y
S
Q
A
S
T
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
Y446
A
N
P
Q
Y
A
V
Y
S
Q
A
S
A
V
S
Rat
Rattus norvegicus
XP_001077680
524
60854
Y446
A
N
P
Q
Y
A
V
Y
S
Q
A
S
A
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512520
524
61016
C446
S
N
P
Q
Y
A
V
C
S
D
T
S
A
L
N
Chicken
Gallus gallus
NP_001072950
524
61120
Y446
S
N
P
Q
Y
P
T
Y
S
D
T
S
L
L
N
Frog
Xenopus laevis
NP_001087638
506
58853
R429
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
N
Zebra Danio
Brachydanio rerio
NP_001038286
578
67245
Y499
S
N
P
Q
F
L
M
Y
I
D
A
N
S
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392477
724
84384
I512
K
G
I
T
N
T
T
I
G
T
I
S
Q
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LF36
492
56491
F418
K
V
I
L
P
I
I
F
P
A
L
E
R
N
T
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
V678
I
F
L
E
T
N
P
V
L
Y
E
N
C
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.5
63.5
97.5
N.A.
96.7
96.9
N.A.
94.2
94.8
80.9
79.2
N.A.
N.A.
54.4
N.A.
N.A.
Protein Similarity:
100
79.1
64.5
97.7
N.A.
97.7
97.5
N.A.
96.7
96.9
83.5
84.5
N.A.
N.A.
63.6
N.A.
N.A.
P-Site Identity:
100
0
93.3
93.3
N.A.
80
86.6
N.A.
46.6
46.6
0
33.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
86.6
N.A.
66.6
66.6
20
73.3
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.3
46.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
0
31
0
0
8
8
47
0
24
0
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% C
% Asp:
8
8
0
0
0
0
0
0
0
24
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
8
8
8
0
8
0
% E
% Phe:
0
8
8
0
8
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
16
0
16
0
0
8
8
8
8
0
8
0
0
0
0
% I
% Lys:
16
0
0
0
0
0
0
8
0
0
16
0
8
0
8
% K
% Leu:
0
0
8
8
0
16
0
0
8
0
8
8
8
24
0
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
24
0
% M
% Asn:
0
62
0
0
8
8
0
0
8
0
0
16
0
16
24
% N
% Pro:
0
0
62
8
8
8
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
62
8
8
0
0
0
39
0
0
8
8
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
24
0
0
0
8
0
0
0
54
8
0
62
8
0
39
% S
% Thr:
0
0
0
16
8
24
16
0
0
8
16
8
24
0
8
% T
% Val:
0
8
0
0
0
0
47
8
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
54
0
8
54
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _