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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTBP1
All Species:
25.45
Human Site:
Y381
Identified Species:
43.08
UniProt:
Q13363
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13363
NP_001012632.1
440
47535
Y381
L
N
G
A
A
Y
R
Y
P
P
G
V
V
G
V
Chimpanzee
Pan troglodytes
XP_508100
956
103006
Y898
L
N
G
A
T
Y
R
Y
P
P
G
I
V
G
V
Rhesus Macaque
Macaca mulatta
XP_001083191
440
47503
Y381
L
N
G
A
A
Y
R
Y
P
P
G
V
V
G
V
Dog
Lupus familis
XP_855070
369
40480
Q311
H
A
A
W
Y
S
E
Q
A
S
I
E
M
R
E
Cat
Felis silvestris
Mouse
Mus musculus
O88712
441
47726
Y382
N
G
A
A
Y
S
R
Y
P
P
G
V
V
S
V
Rat
Rattus norvegicus
Q9Z2F5
430
46610
Y371
N
G
A
A
Y
S
R
Y
P
P
G
V
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510652
503
54613
Y444
N
G
A
A
Y
S
R
Y
P
P
G
V
V
S
V
Chicken
Gallus gallus
NP_001012908
430
46797
Y371
N
G
A
A
Y
S
R
Y
P
P
G
V
V
S
V
Frog
Xenopus laevis
Q9YHU0
440
47758
Y381
L
N
G
G
A
Y
R
Y
P
Q
G
V
V
S
V
Zebra Danio
Brachydanio rerio
NP_001035480
440
48077
P381
L
N
G
A
Y
R
Y
P
P
G
V
V
S
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46036
476
50719
R381
P
E
G
A
L
H
H
R
A
H
S
T
T
P
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780717
442
48249
N384
G
Q
S
W
S
E
P
N
N
P
S
E
L
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04130
624
66436
Y497
V
V
D
S
S
P
E
Y
P
V
D
S
I
Q
V
Baker's Yeast
Sacchar. cerevisiae
P40510
469
51170
L401
Q
E
N
T
V
R
V
L
Y
I
H
R
N
V
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
99.7
82.7
N.A.
98.6
96.1
N.A.
84.2
93.8
95.4
91.1
N.A.
59.8
N.A.
N.A.
64.9
Protein Similarity:
100
42
100
83.1
N.A.
99
96.8
N.A.
85.8
95.4
97.2
95.4
N.A.
72.6
N.A.
N.A.
77.1
P-Site Identity:
100
86.6
100
0
N.A.
60
60
N.A.
60
60
80
40
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
100
6.6
N.A.
60
60
N.A.
60
60
80
40
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.8
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
36
65
22
0
0
0
15
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
15
0
0
0
8
15
0
0
0
0
15
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
29
43
8
0
0
0
0
0
8
58
0
0
22
8
% G
% His:
8
0
0
0
0
8
8
0
0
8
8
0
0
8
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
36
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
29
36
8
0
0
0
0
8
8
0
0
0
8
8
0
% N
% Pro:
8
0
0
0
0
8
8
8
72
58
0
0
0
8
8
% P
% Gln:
8
8
0
0
0
0
0
8
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
15
58
8
0
0
0
8
0
8
0
% R
% Ser:
0
0
8
8
15
36
0
0
0
8
15
8
8
36
0
% S
% Thr:
0
0
0
8
8
0
0
0
0
0
0
8
8
0
0
% T
% Val:
8
8
0
0
8
0
8
0
0
8
8
58
58
8
65
% V
% Trp:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
43
29
8
65
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _