KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B2
All Species:
18.79
Human Site:
S259
Identified Species:
31.79
UniProt:
Q13367
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13367
NP_004635.2
1082
119059
S259
L
S
P
T
Q
N
E
S
L
L
E
E
N
A
E
Chimpanzee
Pan troglodytes
XP_001159946
1082
119051
S259
L
S
P
T
Q
N
E
S
L
L
E
E
N
A
E
Rhesus Macaque
Macaca mulatta
XP_001082801
1082
119335
S259
L
S
P
T
Q
N
E
S
L
L
E
E
N
A
E
Dog
Lupus familis
XP_860622
983
108630
Y196
L
S
P
T
Q
N
P
Y
V
M
D
P
D
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JME5
1082
119174
S259
L
S
P
T
Q
N
E
S
L
L
E
E
N
P
E
Rat
Rattus norvegicus
P62944
937
104534
D150
V
C
V
A
K
L
H
D
I
N
A
Q
M
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
Q362
L
T
R
Y
A
R
T
Q
F
V
S
P
W
K
E
Chicken
Gallus gallus
XP_001232605
1113
123005
Q285
T
Q
F
L
S
P
N
Q
N
E
S
L
L
E
E
Frog
Xenopus laevis
NP_001085309
1099
121588
T267
M
L
T
R
Y
A
R
T
Q
F
V
S
P
W
L
Zebra Danio
Brachydanio rerio
XP_001921364
1084
120719
I254
T
Q
F
L
N
P
N
I
N
E
S
L
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
S290
D
E
S
S
H
S
S
S
H
S
D
D
G
S
S
Honey Bee
Apis mellifera
XP_624446
1049
117649
F258
T
R
Y
A
R
T
Q
F
I
N
P
N
V
D
N
Nematode Worm
Caenorhab. elegans
NP_492171
896
101071
R109
L
I
R
G
S
A
L
R
V
L
T
S
I
R
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
A22
A
K
V
I
T
R
E
A
A
A
V
A
T
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
87.3
N.A.
94.4
23.9
N.A.
55.8
78
61.5
76.2
N.A.
50.7
53.3
38.3
N.A.
Protein Similarity:
100
99.9
99.2
88.5
N.A.
96.8
42.6
N.A.
68.4
84.7
75.4
85.7
N.A.
65.5
69.5
55
N.A.
P-Site Identity:
100
100
100
40
N.A.
93.3
6.6
N.A.
13.3
6.6
0
6.6
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
33.3
N.A.
26.6
6.6
13.3
6.6
N.A.
40
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
8
15
0
8
8
8
8
8
0
22
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
15
8
8
8
0
% D
% Glu:
0
8
0
0
0
0
36
0
0
15
29
29
0
15
58
% E
% Phe:
0
0
15
0
0
0
0
8
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
8
0
8
0
0
0
0
8
0
% H
% Ile:
0
8
0
8
0
0
0
8
15
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
50
8
0
15
0
8
8
0
29
36
0
15
15
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
36
15
0
15
15
0
8
29
0
8
% N
% Pro:
0
0
36
0
0
15
8
0
0
0
8
15
8
8
0
% P
% Gln:
0
15
0
0
36
0
8
15
8
0
0
8
0
0
0
% Q
% Arg:
0
8
15
8
8
15
8
8
0
0
0
0
0
8
8
% R
% Ser:
0
36
8
8
15
8
8
36
0
8
22
15
0
15
8
% S
% Thr:
22
8
8
36
8
8
8
8
0
0
8
0
8
0
0
% T
% Val:
8
0
15
0
0
0
0
0
15
8
15
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
0
8
8
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _