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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B2
All Species:
33.03
Human Site:
S614
Identified Species:
55.9
UniProt:
Q13367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13367
NP_004635.2
1082
119059
S614
K
P
A
P
V
L
E
S
S
F
K
D
R
D
H
Chimpanzee
Pan troglodytes
XP_001159946
1082
119051
S614
K
P
A
P
V
L
E
S
S
F
K
D
R
D
H
Rhesus Macaque
Macaca mulatta
XP_001082801
1082
119335
S614
K
P
A
P
V
L
E
S
S
F
K
D
R
D
H
Dog
Lupus familis
XP_860622
983
108630
L524
K
D
R
D
H
F
Q
L
G
S
L
S
H
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JME5
1082
119174
S614
K
P
A
P
I
L
E
S
S
F
K
D
R
D
H
Rat
Rattus norvegicus
P62944
937
104534
T478
E
G
F
H
D
E
S
T
Q
V
Q
L
T
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
S717
K
P
A
P
L
L
E
S
P
F
R
D
R
D
H
Chicken
Gallus gallus
XP_001232605
1113
123005
S640
K
P
A
P
I
L
E
S
S
F
K
D
R
D
H
Frog
Xenopus laevis
NP_001085309
1099
121588
S622
K
P
A
P
V
L
E
S
S
F
K
D
R
E
H
Zebra Danio
Brachydanio rerio
XP_001921364
1084
120719
S609
K
P
A
P
V
L
E
S
P
F
K
D
R
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
R649
P
V
P
E
S
K
Y
R
D
G
N
N
F
Q
L
Honey Bee
Apis mellifera
XP_624446
1049
117649
K587
F
D
E
D
G
H
K
K
N
L
P
Q
L
A
K
Nematode Worm
Caenorhab. elegans
NP_492171
896
101071
C437
I
A
A
Q
A
R
A
C
V
I
W
L
V
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
T350
L
V
R
T
V
T
M
T
E
N
Q
G
N
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
87.3
N.A.
94.4
23.9
N.A.
55.8
78
61.5
76.2
N.A.
50.7
53.3
38.3
N.A.
Protein Similarity:
100
99.9
99.2
88.5
N.A.
96.8
42.6
N.A.
68.4
84.7
75.4
85.7
N.A.
65.5
69.5
55
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
0
N.A.
80
93.3
93.3
93.3
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
20
N.A.
93.3
100
100
93.3
N.A.
6.6
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
65
0
8
0
8
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
15
8
0
0
0
8
0
0
58
0
50
0
% D
% Glu:
8
0
8
8
0
8
58
0
8
0
0
0
0
8
8
% E
% Phe:
8
0
8
0
0
8
0
0
0
58
0
0
8
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
8
8
0
8
0
0
0
% G
% His:
0
0
0
8
8
8
0
0
0
0
0
0
8
0
58
% H
% Ile:
8
0
0
0
15
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
65
0
0
0
0
8
8
8
0
0
50
0
0
8
8
% K
% Leu:
8
0
0
0
8
58
0
8
0
8
8
15
8
15
22
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
8
8
8
0
0
% N
% Pro:
8
58
8
58
0
0
0
0
15
0
8
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
8
0
15
8
0
8
0
% Q
% Arg:
0
0
15
0
0
8
0
8
0
0
8
0
58
0
0
% R
% Ser:
0
0
0
0
8
0
8
58
43
8
0
8
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
15
0
0
0
0
8
0
8
% T
% Val:
0
15
0
0
43
0
0
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _