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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B2
All Species:
23.64
Human Site:
S716
Identified Species:
40
UniProt:
Q13367
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13367
NP_004635.2
1082
119059
S716
S
G
S
G
E
S
S
S
E
S
D
N
E
D
Q
Chimpanzee
Pan troglodytes
XP_001159946
1082
119051
S716
S
G
S
G
E
S
S
S
E
S
D
N
E
D
Q
Rhesus Macaque
Macaca mulatta
XP_001082801
1082
119335
S716
S
G
S
G
E
S
S
S
E
S
D
N
E
D
Q
Dog
Lupus familis
XP_860622
983
108630
E626
D
S
E
D
Q
E
E
E
K
G
K
S
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JME5
1082
119174
S716
S
G
S
G
E
S
S
S
E
S
D
N
E
E
E
Rat
Rattus norvegicus
P62944
937
104534
A580
V
Y
H
K
P
P
N
A
F
V
E
G
S
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
S819
S
G
K
K
D
S
S
S
E
D
S
S
E
D
S
Chicken
Gallus gallus
XP_001232605
1113
123005
S742
S
G
T
S
S
S
S
S
E
E
E
D
E
E
E
Frog
Xenopus laevis
NP_001085309
1099
121588
Q724
E
K
E
S
S
S
E
Q
S
D
A
S
S
S
A
Zebra Danio
Brachydanio rerio
XP_001921364
1084
120719
R711
S
E
E
S
R
S
A
R
S
G
S
E
S
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
S751
S
G
S
G
T
S
D
S
E
S
D
S
D
G
S
Honey Bee
Apis mellifera
XP_624446
1049
117649
E689
E
E
S
V
Q
A
D
E
L
N
N
E
N
E
S
Nematode Worm
Caenorhab. elegans
NP_492171
896
101071
P539
E
I
F
M
S
K
K
P
A
P
E
L
I
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
K452
S
W
E
S
H
V
M
K
W
L
I
D
H
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
87.3
N.A.
94.4
23.9
N.A.
55.8
78
61.5
76.2
N.A.
50.7
53.3
38.3
N.A.
Protein Similarity:
100
99.9
99.2
88.5
N.A.
96.8
42.6
N.A.
68.4
84.7
75.4
85.7
N.A.
65.5
69.5
55
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
0
N.A.
53.3
46.6
6.6
13.3
N.A.
60
6.6
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
20
N.A.
66.6
80
13.3
26.6
N.A.
73.3
40
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
8
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
15
0
0
15
36
15
8
29
8
% D
% Glu:
22
15
29
0
29
8
15
15
50
8
22
15
43
36
22
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
50
0
36
0
0
0
0
0
15
0
8
0
8
8
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
8
8
15
0
8
8
8
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
8
29
8
0
0
% N
% Pro:
0
0
0
0
8
8
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
8
0
0
0
0
0
0
22
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
65
8
43
29
22
65
43
50
15
36
15
29
29
15
36
% S
% Thr:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _