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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B2
All Species:
35.76
Human Site:
T446
Identified Species:
60.51
UniProt:
Q13367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13367
NP_004635.2
1082
119059
T446
N
I
G
R
V
R
D
T
C
L
N
G
L
V
Q
Chimpanzee
Pan troglodytes
XP_001159946
1082
119051
T446
N
I
G
R
V
R
D
T
C
L
N
G
L
V
Q
Rhesus Macaque
Macaca mulatta
XP_001082801
1082
119335
T446
N
I
G
R
V
R
D
T
C
L
N
G
L
V
Q
Dog
Lupus familis
XP_860622
983
108630
M376
V
I
K
K
L
L
Q
M
Q
P
A
Q
H
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JME5
1082
119174
T446
N
I
G
R
V
R
D
T
C
L
N
G
L
V
Q
Rat
Rattus norvegicus
P62944
937
104534
D330
V
F
F
V
K
Y
N
D
P
I
Y
V
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
T549
N
I
S
E
V
T
D
T
C
L
N
G
L
V
C
Chicken
Gallus gallus
XP_001232605
1113
123005
T472
N
I
G
K
V
R
D
T
C
L
N
G
L
V
Q
Frog
Xenopus laevis
NP_001085309
1099
121588
T454
N
I
S
A
V
T
D
T
C
L
N
G
L
V
Y
Zebra Danio
Brachydanio rerio
XP_001921364
1084
120719
T441
N
I
G
E
V
R
D
T
C
L
N
G
L
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
T477
S
I
K
E
V
T
E
T
C
L
S
G
L
V
H
Honey Bee
Apis mellifera
XP_624446
1049
117649
T439
N
I
K
E
V
T
D
T
C
L
N
G
L
V
S
Nematode Worm
Caenorhab. elegans
NP_492171
896
101071
P289
L
V
R
L
L
R
G
P
R
E
T
Q
Y
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
D202
I
L
K
E
L
M
A
D
T
D
P
K
V
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
87.3
N.A.
94.4
23.9
N.A.
55.8
78
61.5
76.2
N.A.
50.7
53.3
38.3
N.A.
Protein Similarity:
100
99.9
99.2
88.5
N.A.
96.8
42.6
N.A.
68.4
84.7
75.4
85.7
N.A.
65.5
69.5
55
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
0
N.A.
73.3
93.3
73.3
93.3
N.A.
53.3
73.3
13.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
26.6
N.A.
73.3
100
73.3
93.3
N.A.
73.3
73.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
65
15
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
36
0
0
8
0
0
8
0
0
0
0
15
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
43
0
0
0
8
0
0
0
0
72
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
8
79
0
0
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
29
15
8
0
0
0
0
0
0
8
8
0
0
% K
% Leu:
8
8
0
8
22
8
0
0
0
72
0
0
72
8
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
65
0
0
0
0
0
8
0
0
0
65
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
15
0
0
43
% Q
% Arg:
0
0
8
29
0
50
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
0
15
0
0
0
0
0
0
0
8
0
0
0
15
% S
% Thr:
0
0
0
0
0
29
0
72
8
0
8
0
0
0
0
% T
% Val:
15
8
0
8
72
0
0
0
0
0
0
8
8
79
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _