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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE3B
All Species:
5.15
Human Site:
S1053
Identified Species:
10.3
UniProt:
Q13370
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13370
NP_000913.2
1112
124333
S1053
P
K
P
P
R
R
K
S
R
R
R
I
F
C
Q
Chimpanzee
Pan troglodytes
XP_520783
1141
125048
K1067
S
P
K
K
K
T
F
K
R
R
K
I
Y
C
Q
Rhesus Macaque
Macaca mulatta
XP_001092891
1117
125088
S1053
P
K
P
P
R
R
K
S
R
R
Q
I
F
C
Q
Dog
Lupus familis
XP_854529
779
87136
E743
K
E
I
I
E
E
E
E
K
C
K
A
D
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61409
1100
122135
G1035
P
K
P
Q
R
R
K
G
R
R
R
I
F
C
Q
Rat
Rattus norvegicus
Q63085
1108
123088
G1044
P
K
P
Q
R
R
K
G
R
R
R
I
F
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518516
340
38206
L304
W
S
N
E
N
D
R
L
L
V
C
Q
V
C
I
Chicken
Gallus gallus
NP_001026353
1105
121291
K1038
I
L
K
A
Q
R
R
K
G
R
R
I
F
C
Q
Frog
Xenopus laevis
NP_001088828
985
108702
A949
E
E
E
E
K
S
K
A
E
Q
T
K
Q
Q
N
Zebra Danio
Brachydanio rerio
XP_691883
1107
124050
R1035
L
E
P
K
R
R
K
R
R
R
R
L
F
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0P7
625
69850
T589
G
S
Y
E
A
Q
I
T
C
N
G
G
T
A
V
Sea Urchin
Strong. purpuratus
XP_793920
1558
171759
K1443
L
K
S
A
G
Q
Q
K
T
R
K
M
V
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
96.7
60.6
N.A.
81.5
80.6
N.A.
22.4
63.6
59.7
63.2
N.A.
N.A.
N.A.
26.5
28.2
Protein Similarity:
100
58.2
98.2
64.5
N.A.
86.9
86.7
N.A.
26.9
75
70.8
75.5
N.A.
N.A.
N.A.
38.2
41.8
P-Site Identity:
100
33.3
93.3
0
N.A.
86.6
86.6
N.A.
6.6
46.6
6.6
60
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
53.3
100
26.6
N.A.
86.6
86.6
N.A.
13.3
60
33.3
73.3
N.A.
N.A.
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
0
0
9
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
9
9
0
0
67
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
25
9
25
9
9
9
9
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
50
0
0
% F
% Gly:
9
0
0
0
9
0
0
17
9
0
9
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
0
0
9
0
0
0
0
50
0
0
17
% I
% Lys:
9
42
17
17
17
0
50
25
9
0
25
9
0
0
0
% K
% Leu:
17
9
0
0
0
0
0
9
9
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
9
0
0
0
0
25
% N
% Pro:
34
9
42
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
9
17
9
0
0
9
9
9
9
9
50
% Q
% Arg:
0
0
0
0
42
50
17
9
50
67
42
0
0
0
0
% R
% Ser:
9
17
9
0
0
9
0
17
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
9
0
9
9
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
17
0
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _