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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE3B
All Species:
16.36
Human Site:
T1035
Identified Species:
32.73
UniProt:
Q13370
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13370
NP_000913.2
1112
124333
T1035
E
D
G
E
E
L
D
T
E
D
E
E
M
E
N
Chimpanzee
Pan troglodytes
XP_520783
1141
125048
P1049
E
E
E
E
A
A
A
P
N
E
E
E
T
C
E
Rhesus Macaque
Macaca mulatta
XP_001092891
1117
125088
T1035
E
D
G
E
E
L
D
T
D
D
E
E
M
E
N
Dog
Lupus familis
XP_854529
779
87136
L728
F
C
Q
L
M
H
H
L
S
E
N
H
K
I
W
Cat
Felis silvestris
Mouse
Mus musculus
Q61409
1100
122135
S1017
D
G
G
E
E
L
D
S
D
D
E
E
T
E
D
Rat
Rattus norvegicus
Q63085
1108
123088
S1026
D
D
D
E
E
L
D
S
D
D
E
E
T
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518516
340
38206
D289
E
F
N
A
K
A
N
D
V
N
S
S
G
I
E
Chicken
Gallus gallus
NP_001026353
1105
121291
S1021
D
D
G
A
Q
L
E
S
D
D
E
E
I
G
D
Frog
Xenopus laevis
NP_001088828
985
108702
H934
I
H
H
L
R
E
N
H
K
V
W
K
K
T
I
Zebra Danio
Brachydanio rerio
XP_691883
1107
124050
E1020
E
T
E
D
N
E
T
E
D
E
E
L
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0P7
625
69850
E574
H
N
H
R
K
W
K
E
Q
I
E
L
E
N
G
Sea Urchin
Strong. purpuratus
XP_793920
1558
171759
D1422
D
D
D
D
D
D
D
D
N
D
E
E
S
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
96.7
60.6
N.A.
81.5
80.6
N.A.
22.4
63.6
59.7
63.2
N.A.
N.A.
N.A.
26.5
28.2
Protein Similarity:
100
58.2
98.2
64.5
N.A.
86.9
86.7
N.A.
26.9
75
70.8
75.5
N.A.
N.A.
N.A.
38.2
41.8
P-Site Identity:
100
26.6
93.3
0
N.A.
60
60
N.A.
6.6
40
0
20
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
100
40
100
6.6
N.A.
86.6
86.6
N.A.
26.6
86.6
20
46.6
N.A.
N.A.
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
17
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
34
42
17
17
9
9
42
17
42
50
0
0
9
0
42
% D
% Glu:
42
9
17
42
34
17
9
17
9
25
75
59
9
42
17
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
34
0
0
0
0
0
0
0
0
0
9
9
9
% G
% His:
9
9
17
0
0
9
9
9
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
9
17
9
% I
% Lys:
0
0
0
0
17
0
9
0
9
0
0
9
17
0
0
% K
% Leu:
0
0
0
17
0
42
0
9
0
0
0
17
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
9
9
0
9
0
17
0
17
9
9
0
0
17
17
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
25
9
0
9
9
9
0
0
% S
% Thr:
0
9
0
0
0
0
9
17
0
0
0
0
25
9
0
% T
% Val:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _