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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE3B
All Species:
30
Human Site:
Y960
Identified Species:
60
UniProt:
Q13370
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13370
NP_000913.2
1112
124333
Y960
E
G
I
V
N
E
F
Y
E
Q
G
D
E
E
A
Chimpanzee
Pan troglodytes
XP_520783
1141
125048
Y973
D
G
I
V
N
E
F
Y
E
Q
G
D
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001092891
1117
125088
Y960
E
G
I
V
N
E
F
Y
E
Q
G
D
E
E
A
Dog
Lupus familis
XP_854529
779
87136
H657
L
Q
E
S
F
I
T
H
I
V
G
P
L
C
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61409
1100
122135
Y936
E
G
I
V
N
E
F
Y
E
Q
G
D
E
E
A
Rat
Rattus norvegicus
Q63085
1108
123088
Y942
E
G
I
V
N
E
F
Y
E
Q
G
D
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518516
340
38206
Q218
L
V
A
T
N
A
P
Q
A
V
L
Y
N
D
R
Chicken
Gallus gallus
NP_001026353
1105
121291
Y948
E
G
I
V
N
E
F
Y
E
Q
G
D
E
E
A
Frog
Xenopus laevis
NP_001088828
985
108702
H863
L
Q
E
S
F
I
T
H
I
V
G
P
L
C
N
Zebra Danio
Brachydanio rerio
XP_691883
1107
124050
Y949
E
G
I
V
N
E
F
Y
E
Q
G
D
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0P7
625
69850
Q503
I
C
E
E
F
Y
E
Q
G
D
D
E
R
R
R
Sea Urchin
Strong. purpuratus
XP_793920
1558
171759
Y1323
Y
R
I
S
E
E
F
Y
E
Q
G
D
D
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
96.7
60.6
N.A.
81.5
80.6
N.A.
22.4
63.6
59.7
63.2
N.A.
N.A.
N.A.
26.5
28.2
Protein Similarity:
100
58.2
98.2
64.5
N.A.
86.9
86.7
N.A.
26.9
75
70.8
75.5
N.A.
N.A.
N.A.
38.2
41.8
P-Site Identity:
100
93.3
100
6.6
N.A.
100
100
N.A.
6.6
100
6.6
93.3
N.A.
N.A.
N.A.
0
60
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
13.3
100
13.3
93.3
N.A.
N.A.
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
50
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
9
9
67
9
9
0
% D
% Glu:
50
0
25
9
9
67
9
0
67
0
0
9
59
67
0
% E
% Phe:
0
0
0
0
25
0
67
0
0
0
0
0
0
0
0
% F
% Gly:
0
59
0
0
0
0
0
0
9
0
84
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
9
0
67
0
0
17
0
0
17
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
67
0
0
0
0
0
0
0
9
0
17
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
17
0
0
0
% P
% Gln:
0
17
0
0
0
0
0
17
0
67
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
25
% R
% Ser:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
59
0
0
0
0
0
25
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
67
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _