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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK8IP2
All Species:
6.97
Human Site:
T494
Identified Species:
15.33
UniProt:
Q13387
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13387
NP_036456.1
824
87975
T494
G
S
P
G
G
R
G
T
G
P
S
A
P
R
D
Chimpanzee
Pan troglodytes
XP_001142967
824
88027
T494
G
P
P
G
G
R
G
T
G
P
S
A
P
R
D
Rhesus Macaque
Macaca mulatta
XP_001113009
673
74147
V376
S
V
K
Y
T
L
V
V
D
E
H
A
Q
L
E
Dog
Lupus familis
XP_538304
824
88343
R497
G
R
P
G
G
R
P
R
G
P
T
A
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERE9
830
89881
T500
V
P
P
G
S
R
T
T
G
S
T
A
P
L
D
Rat
Rattus norvegicus
Q9R237
708
77300
D411
S
D
S
A
T
V
Y
D
N
C
A
S
A
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421126
604
67559
V307
D
E
S
D
S
A
T
V
Y
D
N
C
V
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685086
697
79382
D400
G
L
S
T
I
C
D
D
D
V
A
D
E
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W0K0
490
53797
A193
G
G
G
G
I
P
P
A
V
R
S
G
Q
Q
R
Honey Bee
Apis mellifera
XP_392444
500
54929
N203
S
S
L
A
D
E
L
N
A
A
T
G
S
N
S
Nematode Worm
Caenorhab. elegans
NP_001033331
522
58328
M225
A
L
L
R
R
I
P
M
A
S
I
P
P
N
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
38.5
89.1
N.A.
88.4
33.7
N.A.
N.A.
34
N.A.
36.5
N.A.
25.4
25.6
21.1
N.A.
Protein Similarity:
100
99.6
51
91.2
N.A.
90.5
47.2
N.A.
N.A.
48
N.A.
49.3
N.A.
37.2
37
34
N.A.
P-Site Identity:
100
93.3
6.6
60
N.A.
53.3
0
N.A.
N.A.
0
N.A.
13.3
N.A.
20
6.6
6.6
N.A.
P-Site Similarity:
100
93.3
13.3
66.6
N.A.
60
13.3
N.A.
N.A.
6.6
N.A.
20
N.A.
26.6
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
0
10
0
10
19
10
19
46
10
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
0
% C
% Asp:
10
10
0
10
10
0
10
19
19
10
0
10
0
10
46
% D
% Glu:
0
10
0
0
0
10
0
0
0
10
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
46
10
10
46
28
0
19
0
37
0
0
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
19
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
19
0
0
10
10
0
0
0
0
0
0
28
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
10
0
0
19
0
% N
% Pro:
0
19
37
0
0
10
28
0
0
28
0
10
37
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
19
10
0
% Q
% Arg:
0
10
0
10
10
37
0
10
0
10
0
0
0
19
10
% R
% Ser:
28
19
28
0
19
0
0
0
0
19
28
10
10
19
28
% S
% Thr:
0
0
0
10
19
0
19
28
0
0
28
0
10
0
0
% T
% Val:
10
10
0
0
0
10
10
19
10
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _