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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 25.86
Human Site: S2 Identified Species: 37.93
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S2 _ _ _ _ _ _ M S L K N E P R V
Chimpanzee Pan troglodytes XP_526380 1125 128795 S91 T L S K V N M S L K N E P R V
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S2 _ _ _ _ _ _ M S L K T E S R V
Dog Lupus familis XP_545291 1075 123911 S2 _ _ _ _ _ _ M S L K N E P R V
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S2 _ _ _ _ _ _ M S L K S E T R V
Rat Rattus norvegicus P70496 1074 123795 S2 _ _ _ _ _ _ M S L R S E A R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 S2 _ _ _ _ _ _ M S L K H E G H A
Frog Xenopus laevis NP_001129642 1039 119219 S2 _ _ _ _ _ _ M S L K L E R S I
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 D3 _ _ _ _ _ M S D S V E N L D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 L153 L P E F Q F S L V D S E Y D E
Honey Bee Apis mellifera XP_001121004 1135 129725 R9 S N N I L N E R R T E N V M D
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 R78 P S N L N V R R D S K T V H I
Sea Urchin Strong. purpuratus XP_784455 790 90080
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 T3 _ _ _ _ _ M S T D K L L L P N
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 L41 E L E N Q E V L R Q L P E N G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 60 77.7 100 N.A. 77.7 66.6 N.A. 0 55.5 55.5 0 N.A. 6.6 0 0 0
P-Site Similarity: 100 60 77.7 100 N.A. 88.8 88.8 N.A. 0 66.6 66.6 0 N.A. 20 6.6 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 10 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 13 7 0 0 0 13 7 % D
% Glu: 7 0 13 0 0 7 7 0 0 0 13 57 7 0 7 % E
% Phe: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 13 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 0 7 0 0 0 0 0 50 7 0 0 0 0 % K
% Leu: 7 13 0 7 7 0 0 13 50 0 19 7 13 0 0 % L
% Met: 0 0 0 0 0 13 50 0 0 0 0 0 0 7 0 % M
% Asn: 0 7 13 7 7 13 0 0 0 0 19 13 0 7 7 % N
% Pro: 7 7 0 0 0 0 0 0 0 0 0 7 19 7 0 % P
% Gln: 0 0 0 0 13 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 13 13 7 0 0 7 38 0 % R
% Ser: 7 7 7 0 0 0 19 50 7 7 19 0 7 7 0 % S
% Thr: 7 0 0 0 0 0 0 7 0 7 7 7 7 0 7 % T
% Val: 0 0 0 0 7 7 7 0 7 7 0 0 13 0 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 57 57 57 57 57 44 0 0 0 0 0 0 0 0 0 % _