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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
48.48
Human Site:
S260
Identified Species:
71.11
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
S260
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
S349
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
S260
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Dog
Lupus familis
XP_545291
1075
123911
S260
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
S260
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Rat
Rattus norvegicus
P70496
1074
123795
S260
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
S258
R
W
L
V
V
K
D
S
F
L
L
Y
M
K
P
Frog
Xenopus laevis
NP_001129642
1039
119219
S261
R
W
L
V
V
K
D
S
F
L
L
Y
M
K
L
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
S255
R
W
L
I
V
K
D
S
F
L
L
Y
M
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
T498
R
W
F
F
V
K
E
T
C
F
G
Y
I
R
P
Honey Bee
Apis mellifera
XP_001121004
1135
129725
T289
R
H
L
V
V
K
D
T
F
V
A
Y
I
R
P
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
S435
R
W
L
M
V
R
D
S
F
V
A
Y
M
D
H
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
S91
E
G
W
V
M
K
R
S
G
G
R
R
V
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
G262
V
W
A
V
L
K
P
G
F
L
A
L
L
E
D
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
R382
Y
K
E
M
V
K
E
R
N
V
M
E
K
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
93.3
86.6
100
N.A.
40
53.3
60
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
93.3
100
N.A.
66.6
86.6
80
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
19
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
69
0
0
0
0
0
0
7
7
% D
% Glu:
7
0
7
0
0
0
13
0
0
0
0
7
0
7
0
% E
% Phe:
0
0
7
7
0
0
0
0
75
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
7
7
7
7
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
44
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
7
0
0
0
88
0
0
0
0
0
0
7
63
0
% K
% Leu:
0
0
69
0
7
0
0
0
0
63
57
7
7
0
13
% L
% Met:
0
0
0
13
7
0
0
0
0
0
7
0
63
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
63
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
75
0
0
0
0
7
7
7
0
0
7
7
0
13
0
% R
% Ser:
0
0
0
0
0
0
0
69
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% T
% Val:
7
0
0
32
82
0
0
0
0
19
0
0
7
0
0
% V
% Trp:
0
75
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _