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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 20.3
Human Site: S508 Identified Species: 29.78
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S508 K R V T S G P S L G S L P P A
Chimpanzee Pan troglodytes XP_526380 1125 128795 L571 A F V G G I D L A Y G R W D D
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S508 K R V T S G P S L G S L P P A
Dog Lupus familis XP_545291 1075 123911 S508 K R V T G G L S S L G S F T A
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S508 K R V T S G L S L G S L T A A
Rat Rattus norvegicus P70496 1074 123795 S508 K R V T S G Q S L G S L T A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 S506 K R M G A V K S L S D L P D A
Frog Xenopus laevis NP_001129642 1039 119219 G486 G G I D L A Y G R W D D D E H
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 S468 K I V V I D Q S V A F V G G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 S745 S T S S F S G S T R R T P S L
Honey Bee Apis mellifera XP_001121004 1135 129725 P537 H Q S S I Y I P S K G K F T N
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 V685 Q Y S G A H Q V A T N M A S G
Sea Urchin Strong. purpuratus XP_784455 790 90080 D301 D I C Y G R W D D F R H R L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 E478 I Y L W S H H E K I V I V D Y
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 Y693 F L V D G R D Y F W S L S E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 6.6 100 46.6 N.A. 80 80 N.A. 0 46.6 0 20 N.A. 13.3 0 0 0
P-Site Similarity: 100 6.6 100 46.6 N.A. 80 80 N.A. 0 60 6.6 33.3 N.A. 20 13.3 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 13 7 0 0 13 7 0 0 7 13 44 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 13 0 7 13 7 7 0 13 7 7 19 7 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 0 0 0 13 0 % E
% Phe: 7 7 0 0 7 0 0 0 7 7 7 0 13 0 0 % F
% Gly: 7 7 0 19 25 32 7 7 0 25 19 0 7 7 7 % G
% His: 7 0 0 0 0 13 7 0 0 0 0 7 0 0 7 % H
% Ile: 7 13 7 0 13 7 7 0 0 7 0 7 0 0 7 % I
% Lys: 44 0 0 0 0 0 7 0 7 7 0 7 0 0 0 % K
% Leu: 0 7 7 0 7 0 13 7 32 7 0 38 0 7 7 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 13 7 0 0 0 0 25 13 0 % P
% Gln: 7 7 0 0 0 0 19 0 0 0 0 0 0 0 0 % Q
% Arg: 0 38 0 0 0 13 0 0 7 7 13 7 7 0 0 % R
% Ser: 7 0 19 13 32 7 0 50 13 7 32 7 7 13 0 % S
% Thr: 0 7 0 32 0 0 0 0 7 7 0 7 13 13 0 % T
% Val: 0 0 50 7 0 7 0 7 7 0 7 7 7 0 7 % V
% Trp: 0 0 0 7 0 0 7 0 0 13 0 0 7 0 0 % W
% Tyr: 0 13 0 7 0 7 7 7 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _