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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
13.94
Human Site:
S519
Identified Species:
20.44
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
S519
L
P
P
A
A
M
E
S
M
E
S
L
R
L
K
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
R582
R
W
D
D
N
E
H
R
L
T
D
V
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
S519
L
P
P
A
A
T
E
S
M
E
S
L
S
L
K
Dog
Lupus familis
XP_545291
1075
123911
E519
S
F
T
A
E
T
T
E
S
M
E
S
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
S519
L
T
A
A
S
V
E
S
M
E
S
L
S
L
K
Rat
Rattus norvegicus
P70496
1074
123795
S519
L
T
A
A
S
V
E
S
M
E
S
L
S
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
S517
L
P
D
A
R
A
L
S
L
P
S
F
S
A
N
Frog
Xenopus laevis
NP_001129642
1039
119219
D497
D
D
E
H
R
L
T
D
V
G
S
V
K
R
I
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
Y479
V
G
G
I
D
L
A
Y
G
R
W
D
D
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
K756
T
P
S
L
Y
F
T
K
D
D
T
D
S
A
F
Honey Bee
Apis mellifera
XP_001121004
1135
129725
K548
K
F
T
N
T
S
S
K
K
I
S
C
A
N
I
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
L696
M
A
S
G
L
R
S
L
M
T
A
P
L
T
L
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
D312
H
R
L
V
D
T
G
D
A
C
Y
Q
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
F489
I
V
D
Y
Q
V
C
F
I
G
G
L
D
L
C
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
A704
L
S
E
A
L
L
M
A
K
D
V
I
Y
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
0
86.6
6.6
N.A.
66.6
66.6
N.A.
0
33.3
6.6
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
13.3
86.6
6.6
N.A.
80
80
N.A.
0
40
33.3
20
N.A.
20
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
13
44
13
7
7
7
7
0
7
0
7
13
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
7
% C
% Asp:
7
7
19
7
13
0
0
13
7
13
7
13
13
0
0
% D
% Glu:
0
0
13
0
7
7
25
7
0
25
7
0
0
7
13
% E
% Phe:
0
13
0
0
0
7
0
7
0
0
0
7
0
0
7
% F
% Gly:
0
7
7
7
0
0
7
0
7
13
7
0
7
0
0
% G
% His:
7
0
0
7
0
0
7
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
7
0
0
0
0
7
7
0
7
0
7
13
% I
% Lys:
7
0
0
0
0
0
0
13
13
0
0
0
7
0
25
% K
% Leu:
38
0
7
7
13
19
7
7
13
0
0
32
13
32
13
% L
% Met:
7
0
0
0
0
7
7
0
32
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
0
0
0
0
7
7
% N
% Pro:
0
25
13
0
0
0
0
0
0
7
0
7
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
7
7
0
0
% Q
% Arg:
7
7
0
0
13
7
0
7
0
7
0
0
7
13
0
% R
% Ser:
7
7
13
0
13
7
13
32
7
0
44
7
32
13
0
% S
% Thr:
7
13
13
0
7
19
19
0
0
13
7
0
0
7
0
% T
% Val:
7
7
0
7
0
19
0
0
7
0
7
13
0
0
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
7
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _