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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 23.64
Human Site: S576 Identified Species: 34.67
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S576 H H L H D A D S I S S I D S T
Chimpanzee Pan troglodytes XP_526380 1125 128795 K636 S I D D V D S K L K G I G K P
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S576 H H L H N A D S I S S I E S T
Dog Lupus familis XP_545291 1075 123911 S577 H H L H N V D S I S S I G S A
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S576 H H L H N A D S I S S I D S T
Rat Rattus norvegicus P70496 1074 123795 S576 R N L H N S D S I S S V D S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 S575 H G M H H A D S V S S I D S E
Frog Xenopus laevis NP_001129642 1039 119219 I551 D A V D S S R I R G L G K S K
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 L533 M V G D S V D L P K L K G I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 S822 P G E T P A E S G I A L E G M
Honey Bee Apis mellifera XP_001121004 1135 129725 L604 L N A G D L L L M Q P L E K S
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 A885 A P S M I E K A A K S G M D F
Sea Urchin Strong. purpuratus XP_784455 790 90080 W366 V E G A K Q L W L G K D Y Y N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 Y544 D E L D R R K Y P R M P W H D
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 T761 N V G N I V G T D S L W T K H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 6.6 86.6 73.3 N.A. 93.3 60 N.A. 0 66.6 6.6 6.6 N.A. 13.3 6.6 6.6 0
P-Site Similarity: 100 13.3 100 80 N.A. 100 86.6 N.A. 0 80 20 6.6 N.A. 40 40 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 32 0 7 7 0 7 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 7 25 13 7 44 0 7 0 0 7 25 7 7 % D
% Glu: 0 13 7 0 0 7 7 0 0 0 0 0 19 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 13 19 7 0 0 7 0 7 13 7 13 19 7 7 % G
% His: 32 25 0 38 7 0 0 0 0 0 0 0 0 7 7 % H
% Ile: 0 7 0 0 13 0 0 7 32 7 0 38 0 7 0 % I
% Lys: 0 0 0 0 7 0 13 7 0 19 7 7 7 19 7 % K
% Leu: 7 0 38 0 0 7 13 13 13 0 19 13 0 0 0 % L
% Met: 7 0 7 7 0 0 0 0 7 0 7 0 7 0 7 % M
% Asn: 7 13 0 7 25 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 7 7 0 0 7 0 0 0 13 0 7 7 0 0 7 % P
% Gln: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 0 0 7 7 7 0 7 7 0 0 0 0 0 % R
% Ser: 7 0 7 0 13 13 7 44 0 44 44 0 0 44 7 % S
% Thr: 0 0 0 7 0 0 0 7 0 0 0 0 7 0 19 % T
% Val: 7 13 7 0 7 19 0 0 7 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 7 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _