KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
22.12
Human Site:
S578
Identified Species:
32.44
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
S578
L
H
D
A
D
S
I
S
S
I
D
S
T
S
S
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
K638
D
D
V
D
S
K
L
K
G
I
G
K
P
R
K
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
S578
L
H
N
A
D
S
I
S
S
I
E
S
T
S
S
Dog
Lupus familis
XP_545291
1075
123911
S579
L
H
N
V
D
S
I
S
S
I
G
S
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
S578
L
H
N
A
D
S
I
S
S
I
D
S
T
S
S
Rat
Rattus norvegicus
P70496
1074
123795
S578
L
H
N
S
D
S
I
S
S
V
D
S
A
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
S577
M
H
H
A
D
S
V
S
S
I
D
S
E
S
S
Frog
Xenopus laevis
NP_001129642
1039
119219
G553
V
D
S
S
R
I
R
G
L
G
K
S
K
K
F
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
K535
G
D
S
V
D
L
P
K
L
K
G
I
G
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
I824
E
T
P
A
E
S
G
I
A
L
E
G
M
K
L
Honey Bee
Apis mellifera
XP_001121004
1135
129725
Q606
A
G
D
L
L
L
M
Q
P
L
E
K
S
D
T
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
K887
S
M
I
E
K
A
A
K
S
G
M
D
F
A
S
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
G368
G
A
K
Q
L
W
L
G
K
D
Y
Y
N
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
R546
L
D
R
R
K
Y
P
R
M
P
W
H
D
V
H
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
S763
G
N
I
V
G
T
D
S
L
W
T
K
H
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
6.6
86.6
73.3
N.A.
93.3
73.3
N.A.
0
73.3
6.6
6.6
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
13.3
100
80
N.A.
100
93.3
N.A.
0
86.6
20
13.3
N.A.
40
40
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
32
0
7
7
0
7
0
0
0
13
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
25
13
7
44
0
7
0
0
7
25
7
7
7
0
% D
% Glu:
7
0
0
7
7
0
0
0
0
0
19
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% F
% Gly:
19
7
0
0
7
0
7
13
7
13
19
7
7
0
0
% G
% His:
0
38
7
0
0
0
0
0
0
0
0
7
7
0
7
% H
% Ile:
0
0
13
0
0
7
32
7
0
38
0
7
0
0
7
% I
% Lys:
0
0
7
0
13
7
0
19
7
7
7
19
7
13
7
% K
% Leu:
38
0
0
7
13
13
13
0
19
13
0
0
0
0
7
% L
% Met:
7
7
0
0
0
0
7
0
7
0
7
0
7
0
7
% M
% Asn:
0
7
25
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
7
0
0
0
13
0
7
7
0
0
7
7
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
7
7
0
7
7
0
0
0
0
0
13
0
% R
% Ser:
7
0
13
13
7
44
0
44
44
0
0
44
7
44
44
% S
% Thr:
0
7
0
0
0
7
0
0
0
0
7
0
19
0
13
% T
% Val:
7
0
7
19
0
0
7
0
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
7
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _