Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 23.33
Human Site: S610 Identified Species: 34.22
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S610 H F K L F H P S S E S E Q G L
Chimpanzee Pan troglodytes XP_526380 1125 128795 S668 H N A D S I S S I D S T S N T
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S610 H F K L F R P S S E S E Q G L
Dog Lupus familis XP_545291 1075 123911 S611 H L K L F R S S S K S E Q G L
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S610 H L K L F H P S S E S E Q G L
Rat Rattus norvegicus P70496 1074 123795 S610 H L K L F R P S S E S E Q G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 L609 Y L R M F L H L H S E S Q G S
Frog Xenopus laevis NP_001129642 1039 119219 S582 Q H A D S V S S I D S E S H R
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 S565 H H A D S I S S I D S T N K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 D885 I E S E E A T D H E V N L N M
Honey Bee Apis mellifera XP_001121004 1135 129725 D664 E G S S D E E D T I D N N T V
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 S955 K W K Q M L E S D E A T M G Y
Sea Urchin Strong. purpuratus XP_784455 790 90080 R397 M D R S S V P R L P W H D I A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 S575 F V Q R W N H S K R N K A P N
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 I809 I D E T F A F I G G T D L C Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 20 93.3 73.3 N.A. 93.3 86.6 N.A. 0 20 20 20 N.A. 6.6 0 26.6 6.6
P-Site Similarity: 100 26.6 93.3 80 N.A. 93.3 86.6 N.A. 0 40 26.6 26.6 N.A. 13.3 13.3 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 13 0 0 0 0 7 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 13 0 19 7 0 0 13 7 19 7 7 7 0 0 % D
% Glu: 7 7 7 7 7 7 13 0 0 38 7 38 0 0 0 % E
% Phe: 7 13 0 0 44 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 7 0 0 0 44 0 % G
% His: 44 13 0 0 0 13 13 0 13 0 0 7 0 7 0 % H
% Ile: 13 0 0 0 0 13 0 7 19 7 0 0 0 7 0 % I
% Lys: 7 0 38 0 0 0 0 0 7 7 0 7 0 7 0 % K
% Leu: 0 25 0 32 0 13 0 7 7 0 0 0 13 0 32 % L
% Met: 7 0 0 7 7 0 0 0 0 0 0 0 7 0 7 % M
% Asn: 0 7 0 0 0 7 0 0 0 0 7 13 13 13 7 % N
% Pro: 0 0 0 0 0 0 32 0 0 7 0 0 0 7 0 % P
% Gln: 7 0 7 7 0 0 0 0 0 0 0 0 38 0 0 % Q
% Arg: 0 0 13 7 0 19 0 7 0 7 0 0 0 0 7 % R
% Ser: 0 0 13 13 25 0 25 63 32 7 50 7 13 0 13 % S
% Thr: 0 0 0 7 0 0 7 0 7 0 7 19 0 7 7 % T
% Val: 0 7 0 0 0 13 0 0 0 0 7 0 0 0 7 % V
% Trp: 0 7 0 0 7 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _