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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 33.94
Human Site: S723 Identified Species: 49.78
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S723 Y P F L L P K S Q T T A H E L
Chimpanzee Pan troglodytes XP_526380 1125 128795 S774 Y P F L L P K S Q T T A H E L
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S723 Y P F L L P K S Q T T A H E L
Dog Lupus familis XP_545291 1075 123911 S724 Y P F L L P K S Q T T A H E L
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S723 Y P F L L P K S Q A T A H E L
Rat Rattus norvegicus P70496 1074 123795 S723 Y P F L L P K S Q A T A H E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 S722 Y P F L L P K S Q Q T A N E L
Frog Xenopus laevis NP_001129642 1039 119219 S688 Y P F L L P K S H K T A K E L
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 S671 Y P F L L P K S H S T G N D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 V1001 M P K S Y H Q V R L N P N I Q
Honey Bee Apis mellifera XP_001121004 1135 129725 R781 P K S Y K N C R N F V P F L E
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 E1069 Y L L P K S Y E N V R V P R V
Sea Urchin Strong. purpuratus XP_784455 790 90080 H497 H A I N N S K H Y I Y I E V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 L676 E T S E E S D L D E A V N D W
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 E920 P P S D L T A E E L K S L P M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 86.6 80 66.6 N.A. 6.6 0 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 93.3 80 86.6 N.A. 26.6 0 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 7 0 0 13 7 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 7 0 7 0 0 0 0 13 0 % D
% Glu: 7 0 0 7 7 0 0 13 7 7 0 0 7 50 7 % E
% Phe: 0 0 57 0 0 0 0 0 0 7 0 0 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % G
% His: 7 0 0 0 0 7 0 7 13 0 0 0 38 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 7 0 7 0 7 0 % I
% Lys: 0 7 7 0 13 0 63 0 0 7 7 0 7 0 0 % K
% Leu: 0 7 7 57 63 0 0 7 0 13 0 0 7 7 57 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 7 7 7 0 0 13 0 7 0 25 0 0 % N
% Pro: 13 69 0 7 0 57 0 0 0 0 0 13 7 7 0 % P
% Gln: 0 0 0 0 0 0 7 0 44 7 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 7 7 0 7 0 0 7 7 % R
% Ser: 0 0 19 7 0 19 0 57 0 7 0 7 0 0 0 % S
% Thr: 0 7 0 0 0 7 0 0 0 25 57 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 7 0 7 7 13 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 63 0 0 7 7 0 7 0 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _