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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
37.27
Human Site:
T143
Identified Species:
54.67
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
T143
F
I
R
I
P
I
P
T
R
R
H
T
F
R
R
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
T232
F
I
R
I
P
I
P
T
R
R
H
T
F
R
R
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
T143
F
I
R
I
P
I
P
T
R
R
H
T
F
R
R
Dog
Lupus familis
XP_545291
1075
123911
T143
F
I
R
I
P
I
P
T
R
R
H
T
F
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
T143
F
I
R
I
P
I
P
T
K
R
H
T
F
R
R
Rat
Rattus norvegicus
P70496
1074
123795
T143
F
I
R
I
P
I
P
T
K
R
H
T
F
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
T139
F
V
R
I
P
I
P
T
R
S
H
T
V
R
R
Frog
Xenopus laevis
NP_001129642
1039
119219
I144
F
I
R
I
P
I
P
I
R
S
H
T
V
R
R
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
T135
L
M
R
I
P
L
P
T
R
S
H
T
E
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
S294
S
L
N
I
P
F
P
S
R
S
H
K
E
K
R
Honey Bee
Apis mellifera
XP_001121004
1135
129725
T150
S
L
N
I
P
F
P
T
K
S
H
K
E
R
R
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
R225
P
I
K
R
T
Q
E
R
F
D
N
Y
L
E
H
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
Y142
D
G
A
L
P
L
H
Y
T
E
D
S
I
K
N
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
A183
S
V
N
S
P
T
P
A
G
S
G
H
R
H
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
80
80
66.6
N.A.
40
46.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
80
80
N.A.
60
60
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
7
0
0
19
7
0
% E
% Phe:
50
0
0
0
0
13
0
0
7
0
0
0
38
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
7
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
69
7
0
7
7
% H
% Ile:
0
50
0
69
0
50
0
7
0
0
0
0
7
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
19
0
0
13
0
13
0
% K
% Leu:
7
13
0
7
0
13
0
0
0
0
0
0
7
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
0
0
0
0
0
0
0
7
0
0
0
13
% N
% Pro:
7
0
0
0
82
0
75
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
57
7
0
0
0
7
50
38
0
0
7
63
69
% R
% Ser:
19
0
0
7
0
0
0
7
0
38
0
7
0
0
0
% S
% Thr:
0
0
0
0
7
7
0
57
7
0
0
57
0
0
0
% T
% Val:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _