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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 15.45
Human Site: T624 Identified Species: 22.67
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 T624 L T R P H A D T G S I R S L Q
Chimpanzee Pan troglodytes XP_526380 1125 128795 Q682 T G S I R S L Q T G V G E L H
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 T624 L T R P N A D T G S I R S L Q
Dog Lupus familis XP_545291 1075 123911 T625 L P R P D T D T S S L R S L Q
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 T624 L T R H S T D T G S I R S V Q
Rat Rattus norvegicus P70496 1074 123795 T624 L T R H S A D T G S I R S V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 K623 S W A L P H D K G S I R S L K
Frog Xenopus laevis NP_001129642 1039 119219 Q596 R G S V R S L Q T G V G E L L
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 Q579 S G S V H S L Q T G V G E L M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 V899 M A S G G Q E V A I T T S S T
Honey Bee Apis mellifera XP_001121004 1135 129725 N678 V Q T A I E S N E S V T Y S G
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 L969 Y E L D W L R L R E M D E K G
Sea Urchin Strong. purpuratus XP_784455 790 90080 A411 A A V V H G K A A L D V A R H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 L589 N E Q T I P L L M P H H H M V
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 E823 Y G R Y D T F E H V L R D D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 6.6 93.3 66.6 N.A. 73.3 80 N.A. 0 46.6 6.6 13.3 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 20 100 73.3 N.A. 80 86.6 N.A. 0 53.3 20 26.6 N.A. 20 20 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 7 7 0 19 0 7 13 0 0 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 13 0 38 0 0 0 7 7 7 7 0 % D
% Glu: 0 13 0 0 0 7 7 7 7 7 0 0 25 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 25 0 7 7 7 0 0 32 19 0 19 0 0 13 % G
% His: 0 0 0 13 19 7 0 0 7 0 7 7 7 0 13 % H
% Ile: 0 0 0 7 13 0 0 0 0 7 32 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 7 7 0 0 0 0 0 7 7 % K
% Leu: 32 0 7 7 0 7 25 13 0 7 13 0 0 44 7 % L
% Met: 7 0 0 0 0 0 0 0 7 0 7 0 0 7 7 % M
% Asn: 7 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 19 7 7 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 7 7 0 0 7 0 19 0 0 0 0 0 0 32 % Q
% Arg: 7 0 38 0 13 0 7 0 7 0 0 44 0 7 0 % R
% Ser: 13 0 25 0 13 19 7 0 7 44 0 0 44 13 0 % S
% Thr: 7 25 7 7 0 19 0 32 19 0 7 13 0 0 7 % T
% Val: 7 0 7 19 0 0 0 7 0 7 25 7 0 13 7 % V
% Trp: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _