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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 17.58
Human Site: T725 Identified Species: 25.78
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 T725 F L L P K S Q T T A H E L R Y
Chimpanzee Pan troglodytes XP_526380 1125 128795 T776 F L L P K S Q T T A H E L R Y
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 T725 F L L P K S Q T T A H E L R Y
Dog Lupus familis XP_545291 1075 123911 T726 F L L P K S Q T T A H E L K Y
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 A725 F L L P K S Q A T A H E L R Y
Rat Rattus norvegicus P70496 1074 123795 A725 F L L P K S Q A T A H E L R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 Q724 F L L P K S Q Q T A N E L K Y
Frog Xenopus laevis NP_001129642 1039 119219 K690 F L L P K S H K T A K E L P Y
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 S673 F L L P K S H S T G N D L K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 L1003 K S Y H Q V R L N P N I Q Q N
Honey Bee Apis mellifera XP_001121004 1135 129725 F783 S Y K N C R N F V P F L E E S
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 V1071 L P K S Y E N V R V P R V F K
Sea Urchin Strong. purpuratus XP_784455 790 90080 I499 I N N S K H Y I Y I E V R P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 E678 S E E S D L D E A V N D W W W
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 L922 S D L T A E E L K S L P M F E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 80 73.3 60 N.A. 0 0 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 93.3 73.3 86.6 N.A. 26.6 0 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 13 7 50 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 0 7 0 0 0 0 13 0 0 0 % D
% Glu: 0 7 7 0 0 13 7 7 0 0 7 50 7 7 7 % E
% Phe: 57 0 0 0 0 0 0 7 0 0 7 0 0 13 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 7 0 7 13 0 0 0 38 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 7 0 7 0 7 0 0 0 % I
% Lys: 7 0 13 0 63 0 0 7 7 0 7 0 0 19 7 % K
% Leu: 7 57 63 0 0 7 0 13 0 0 7 7 57 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 7 7 0 0 13 0 7 0 25 0 0 0 7 % N
% Pro: 0 7 0 57 0 0 0 0 0 13 7 7 0 13 0 % P
% Gln: 0 0 0 0 7 0 44 7 0 0 0 0 7 7 0 % Q
% Arg: 0 0 0 0 0 7 7 0 7 0 0 7 7 32 0 % R
% Ser: 19 7 0 19 0 57 0 7 0 7 0 0 0 0 7 % S
% Thr: 0 0 0 7 0 0 0 25 57 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 7 7 13 0 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 7 % W
% Tyr: 0 7 7 0 7 0 7 0 7 0 0 0 0 0 57 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _