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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
33.64
Human Site:
Y295
Identified Species:
49.33
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
Y295
K
K
E
T
E
T
K
Y
G
I
R
I
D
N
L
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
Y384
K
K
E
T
E
T
K
Y
G
I
R
I
D
N
L
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
Y295
K
K
E
T
E
T
K
Y
G
I
R
I
D
N
L
Dog
Lupus familis
XP_545291
1075
123911
Y295
K
K
E
T
E
T
K
Y
G
L
R
I
D
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
Y295
R
K
E
T
E
T
K
Y
G
L
R
I
D
N
L
Rat
Rattus norvegicus
P70496
1074
123795
Y295
K
K
E
T
E
T
K
Y
G
L
R
I
D
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
Y293
Q
K
E
T
E
T
K
Y
G
L
Q
I
D
N
L
Frog
Xenopus laevis
NP_001129642
1039
119219
Y296
K
K
E
T
E
T
K
Y
G
L
R
I
D
N
L
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
Q285
S
I
K
M
D
S
K
Q
T
E
T
K
H
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
K533
I
Y
Q
T
G
M
R
K
G
L
Q
V
L
T
N
Honey Bee
Apis mellifera
XP_001121004
1135
129725
N324
M
Y
T
T
G
L
R
N
G
M
Q
I
A
N
L
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
T471
K
E
T
E
G
I
P
T
G
L
I
I
T
N
S
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
V119
Y
S
K
R
W
L
I
V
K
D
S
F
V
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
Q295
G
T
K
E
S
S
E
Q
P
R
L
A
E
Q
V
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
L456
S
Q
P
I
H
L
R
L
E
R
Y
L
R
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
0
80
93.3
6.6
N.A.
13.3
33.3
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
33.3
N.A.
46.6
53.3
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
7
0
0
50
0
0
% D
% Glu:
0
7
50
13
50
0
7
0
7
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
0
19
0
0
0
69
0
0
0
0
7
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
7
0
7
0
7
7
0
0
19
7
63
0
0
0
% I
% Lys:
44
50
19
0
0
0
57
7
7
0
0
7
0
0
0
% K
% Leu:
0
0
0
0
0
19
0
7
0
44
7
7
7
7
63
% L
% Met:
7
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
63
7
% N
% Pro:
0
0
7
0
0
0
7
0
7
0
0
0
0
0
0
% P
% Gln:
7
7
7
0
0
0
0
13
0
0
19
0
0
7
0
% Q
% Arg:
7
0
0
7
0
0
19
0
0
13
44
0
7
0
0
% R
% Ser:
13
7
0
0
7
13
0
0
0
0
7
0
0
0
7
% S
% Thr:
0
7
13
63
0
50
0
7
7
0
7
0
7
7
0
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
7
7
0
13
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
13
0
0
0
0
0
50
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _