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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
25.45
Human Site:
Y459
Identified Species:
37.33
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
Y459
D
H
V
S
S
T
V
Y
L
W
A
H
H
E
K
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
Y522
A
L
G
I
N
S
E
Y
T
K
R
T
L
M
R
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
Y459
D
H
V
S
S
T
V
Y
L
W
A
H
H
E
K
Dog
Lupus familis
XP_545291
1075
123911
Y459
D
H
V
S
S
S
V
Y
L
W
A
H
H
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
Y459
D
H
V
S
S
S
V
Y
L
W
A
H
H
E
K
Rat
Rattus norvegicus
P70496
1074
123795
Y459
D
H
V
S
S
S
V
Y
L
W
A
H
H
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
Y457
D
H
V
S
S
S
V
Y
L
W
A
H
H
E
K
Frog
Xenopus laevis
NP_001129642
1039
119219
R437
I
N
S
E
Y
S
K
R
T
L
L
R
I
H
P
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
E419
V
M
L
Y
K
E
V
E
L
A
L
G
I
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
L696
D
H
A
R
G
G
I
L
L
W
A
H
H
E
K
Honey Bee
Apis mellifera
XP_001121004
1135
129725
F488
D
H
A
R
V
G
I
F
L
W
A
H
H
E
K
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
F636
H
Y
P
S
T
G
T
F
F
W
A
H
H
E
K
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
P252
L
Q
I
F
L
K
R
P
P
Q
Q
D
N
R
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
Y429
A
K
Q
G
V
K
I
Y
I
L
L
Y
K
E
V
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
C644
E
R
K
L
K
I
I
C
K
S
E
S
S
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
0
93.3
0
13.3
N.A.
60
60
46.6
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
0
100
13.3
20
N.A.
66.6
73.3
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
0
0
0
0
0
0
7
57
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
7
0
0
7
0
7
7
7
0
0
7
0
0
63
0
% E
% Phe:
0
0
0
7
0
0
0
13
7
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
7
19
0
0
0
0
0
7
0
0
0
% G
% His:
7
50
0
0
0
0
0
0
0
0
0
57
57
7
0
% H
% Ile:
7
0
7
7
0
7
25
0
7
0
0
0
13
0
0
% I
% Lys:
0
7
7
0
13
13
7
0
7
7
0
0
7
0
63
% K
% Leu:
7
7
7
7
7
0
0
7
57
13
19
0
7
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
7
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
7
0
0
0
0
7
7
0
0
0
0
0
7
% P
% Gln:
0
7
7
0
0
0
0
0
0
7
7
0
0
0
0
% Q
% Arg:
0
7
0
13
0
0
7
7
0
0
7
7
0
7
7
% R
% Ser:
0
0
7
44
38
38
0
0
0
7
0
7
7
0
7
% S
% Thr:
0
0
0
0
7
13
7
0
13
0
0
7
0
0
0
% T
% Val:
7
0
38
0
13
0
44
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
57
0
0
0
0
7
% W
% Tyr:
0
7
0
7
7
0
0
50
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _