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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC1I2
All Species:
26.97
Human Site:
S121
Identified Species:
59.33
UniProt:
Q13409
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13409
NP_001369.1
638
71457
S121
L
H
W
D
T
D
P
S
V
L
Q
L
H
S
D
Chimpanzee
Pan troglodytes
XP_001144171
650
72685
S133
L
H
W
D
T
D
P
S
V
L
Q
L
H
S
D
Rhesus Macaque
Macaca mulatta
XP_001084340
847
94331
S330
L
H
W
D
T
D
P
S
V
L
Q
L
H
S
D
Dog
Lupus familis
XP_849905
638
71498
S121
L
H
W
D
T
D
P
S
V
L
Q
L
H
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O88487
612
68376
I110
V
G
S
R
R
G
P
I
K
L
G
M
A
K
I
Rat
Rattus norvegicus
Q62871
638
71160
S121
L
H
W
D
T
D
P
S
A
L
Q
L
H
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514464
636
71072
S121
L
H
W
D
T
D
P
S
V
L
Q
L
H
S
D
Chicken
Gallus gallus
NP_001006519
609
68080
G107
G
A
V
G
S
R
R
G
P
V
K
L
G
M
A
Frog
Xenopus laevis
NP_001084812
637
70999
S122
L
H
W
D
T
D
P
S
V
L
Q
L
H
S
D
Zebra Danio
Brachydanio rerio
XP_690115
608
68094
R105
G
D
G
G
T
G
P
R
R
G
P
L
K
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24246
663
73899
V115
L
N
L
S
V
Y
N
V
Q
A
T
N
I
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
69.7
99.5
N.A.
93.8
97.1
N.A.
96.5
91.3
84.9
79.4
N.A.
49.1
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
72.8
99.8
N.A.
94.8
98.5
N.A.
98.1
92.9
91
87.7
N.A.
67.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
93.3
N.A.
100
6.6
100
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
93.3
N.A.
100
26.6
100
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
64
0
64
0
0
0
0
0
0
0
0
64
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
10
19
0
19
0
10
0
10
10
0
10
0
10
% G
% His:
0
64
0
0
0
0
0
0
0
0
0
0
64
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
10
10
0
% K
% Leu:
73
0
10
0
0
0
0
0
0
73
0
82
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
82
0
10
0
10
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
64
0
0
0
0
% Q
% Arg:
0
0
0
10
10
10
10
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
10
0
0
64
0
0
0
0
0
64
0
% S
% Thr:
0
0
0
0
73
0
0
0
0
0
10
0
0
0
0
% T
% Val:
10
0
10
0
10
0
0
10
55
10
0
0
0
0
0
% V
% Trp:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _