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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC2L
All Species:
12.42
Human Site:
S228
Identified Species:
19.52
UniProt:
Q13416
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13416
NP_006181.1
577
65972
S228
P
V
G
K
E
T
P
S
K
R
M
K
R
D
K
Chimpanzee
Pan troglodytes
XP_516023
646
73228
S297
P
V
C
K
E
T
P
S
K
R
M
K
R
D
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536028
577
66097
S228
P
V
C
K
E
T
P
S
K
K
M
K
R
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60862
576
65875
P227
P
V
S
K
E
T
L
P
K
K
K
K
R
D
K
Rat
Rattus norvegicus
Q75PQ8
576
65831
P226
P
V
S
K
E
I
L
P
K
K
R
K
R
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520674
406
46742
L67
K
T
D
P
T
T
D
L
V
V
I
Y
F
E
A
Chicken
Gallus gallus
NP_001006517
569
64216
T220
S
T
P
P
S
R
K
T
L
T
K
K
K
D
N
Frog
Xenopus laevis
Q91628
558
62908
S209
Q
T
P
G
K
T
P
S
K
K
G
K
K
N
T
Zebra Danio
Brachydanio rerio
NP_001070772
553
62538
N205
A
A
L
Y
K
T
P
N
K
K
S
K
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24168
618
68977
A268
A
A
R
L
R
Q
S
A
R
A
K
K
S
N
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21037
430
49301
R91
M
N
N
A
K
S
R
R
G
R
R
A
G
N
G
Sea Urchin
Strong. purpuratus
XP_789987
337
38784
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105071
377
42494
V38
K
E
K
E
P
S
S
V
K
K
R
A
R
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38899
363
40793
L24
N
Y
F
L
A
K
E
L
G
G
A
S
K
R
S
Baker's Yeast
Sacchar. cerevisiae
P32833
620
71220
V221
R
N
F
T
P
T
P
V
P
K
N
K
K
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
N.A.
91.6
N.A.
78.8
78.6
N.A.
55.9
66.7
61
55.6
N.A.
34.9
N.A.
24
35.1
Protein Similarity:
100
87.1
N.A.
95.6
N.A.
88.3
87.8
N.A.
64.8
81.2
77.9
72.7
N.A.
54.3
N.A.
42.9
46.9
P-Site Identity:
100
93.3
N.A.
86.6
N.A.
66.6
60
N.A.
6.6
13.3
33.3
26.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
73.3
66.6
N.A.
20
26.6
60
53.3
N.A.
33.3
N.A.
26.6
0
Percent
Protein Identity:
N.A.
24.9
N.A.
24.9
20.6
N.A.
Protein Similarity:
N.A.
38.6
N.A.
39.5
43
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
7
7
0
0
7
0
7
7
14
0
7
20
% A
% Cys:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
0
0
0
0
0
40
0
% D
% Glu:
0
7
0
7
34
0
7
0
0
0
0
0
0
7
7
% E
% Phe:
0
0
14
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
7
0
0
0
0
14
7
7
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
14
0
7
34
20
7
7
0
54
47
20
67
34
0
34
% K
% Leu:
0
0
7
14
0
0
14
14
7
0
0
0
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% M
% Asn:
7
14
7
0
0
0
0
7
0
0
7
0
0
20
7
% N
% Pro:
34
0
14
14
14
0
40
14
7
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
0
7
7
7
7
7
20
20
0
40
7
0
% R
% Ser:
7
0
14
0
7
14
14
27
0
0
7
7
7
0
7
% S
% Thr:
0
20
0
7
7
54
0
7
0
7
0
0
0
7
7
% T
% Val:
0
34
0
0
0
0
0
14
7
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _