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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC2L
All Species:
38.18
Human Site:
S255
Identified Species:
60
UniProt:
Q13416
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13416
NP_006181.1
577
65972
S255
S
S
S
K
V
L
T
S
D
R
T
L
Q
K
L
Chimpanzee
Pan troglodytes
XP_516023
646
73228
S324
S
S
S
K
V
L
T
S
D
R
T
L
Q
K
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536028
577
66097
S255
S
S
S
K
V
L
T
S
D
R
T
L
Q
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60862
576
65875
S254
S
S
S
K
V
L
T
S
D
R
T
L
Q
R
L
Rat
Rattus norvegicus
Q75PQ8
576
65831
S253
S
S
S
K
V
L
T
S
D
R
T
L
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520674
406
46742
K94
L
Q
K
L
Q
R
A
K
L
D
Q
Q
T
L
R
Chicken
Gallus gallus
NP_001006517
569
64216
S247
S
S
S
K
V
L
T
S
D
R
T
L
Q
K
L
Frog
Xenopus laevis
Q91628
558
62908
S236
S
S
S
K
V
L
T
S
D
R
T
L
Q
R
L
Zebra Danio
Brachydanio rerio
NP_001070772
553
62538
S232
S
S
S
K
V
L
T
S
D
R
T
L
Q
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24168
618
68977
S295
A
S
S
K
I
L
T
S
D
H
T
L
D
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21037
430
49301
K118
N
A
I
T
D
F
T
K
C
D
L
P
G
L
R
Sea Urchin
Strong. purpuratus
XP_789987
337
38784
T25
H
T
L
S
R
L
D
T
P
Q
M
G
S
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105071
377
42494
A65
Q
V
L
R
A
S
L
A
Q
I
P
P
K
H
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38899
363
40793
S51
Q
E
L
R
E
T
A
S
T
I
E
M
K
H
S
Baker's Yeast
Sacchar. cerevisiae
P32833
620
71220
D248
D
T
F
E
G
Y
F
D
Q
R
K
I
V
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
N.A.
91.6
N.A.
78.8
78.6
N.A.
55.9
66.7
61
55.6
N.A.
34.9
N.A.
24
35.1
Protein Similarity:
100
87.1
N.A.
95.6
N.A.
88.3
87.8
N.A.
64.8
81.2
77.9
72.7
N.A.
54.3
N.A.
42.9
46.9
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
0
100
93.3
93.3
N.A.
66.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
86.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
24.9
N.A.
24.9
20.6
N.A.
Protein Similarity:
N.A.
38.6
N.A.
39.5
43
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
14
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
7
7
60
14
0
0
7
0
0
% D
% Glu:
0
7
0
7
7
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
7
0
0
7
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
7
7
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
7
0
0
0
14
0
% H
% Ile:
0
0
7
0
7
0
0
0
0
14
0
7
0
0
0
% I
% Lys:
0
0
7
60
0
0
0
14
0
0
7
0
14
34
7
% K
% Leu:
7
0
20
7
0
67
7
0
7
0
7
60
0
14
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
7
14
0
0
0
% P
% Gln:
14
7
0
0
7
0
0
0
14
7
7
7
54
0
7
% Q
% Arg:
0
0
0
14
7
7
0
0
0
60
0
0
0
34
14
% R
% Ser:
54
60
60
7
0
7
0
67
0
0
0
0
7
0
7
% S
% Thr:
0
14
0
7
0
7
67
7
7
0
60
0
7
0
7
% T
% Val:
0
7
0
0
54
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _