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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC2L
All Species:
22.73
Human Site:
Y451
Identified Species:
35.71
UniProt:
Q13416
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13416
NP_006181.1
577
65972
Y451
L
W
Y
E
T
T
T
Y
S
P
Y
T
E
E
T
Chimpanzee
Pan troglodytes
XP_516023
646
73228
Y520
L
W
Y
E
T
T
T
Y
S
P
Y
T
E
E
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536028
577
66097
Y451
L
W
Y
E
T
T
T
Y
S
P
Y
T
E
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60862
576
65875
Y450
L
W
Y
E
T
T
T
Y
S
P
Y
T
E
E
T
Rat
Rattus norvegicus
Q75PQ8
576
65831
Y449
L
W
Y
E
T
T
T
Y
S
P
Y
T
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520674
406
46742
I283
T
T
T
Y
N
P
Y
I
E
E
T
S
Y
E
N
Chicken
Gallus gallus
NP_001006517
569
64216
F443
L
W
Y
E
T
T
T
F
S
P
Y
V
E
E
T
Frog
Xenopus laevis
Q91628
558
62908
F432
L
W
Y
E
T
T
T
F
G
S
Y
I
E
E
T
Zebra Danio
Brachydanio rerio
NP_001070772
553
62538
Y428
L
W
F
E
S
T
T
Y
R
S
Y
T
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24168
618
68977
M493
S
W
W
D
C
T
T
M
L
P
Y
T
N
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21037
430
49301
T307
I
P
L
Q
E
L
M
T
G
D
S
R
L
L
G
Sea Urchin
Strong. purpuratus
XP_789987
337
38784
D214
W
Y
D
V
T
T
F
D
P
Y
T
D
E
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105071
377
42494
V254
F
K
W
S
W
Y
H
V
P
T
F
A
P
Y
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38899
363
40793
P240
N
W
L
W
H
H
V
P
T
F
A
P
Y
N
V
Baker's Yeast
Sacchar. cerevisiae
P32833
620
71220
F483
V
F
H
D
I
S
N
F
E
P
S
T
V
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
N.A.
91.6
N.A.
78.8
78.6
N.A.
55.9
66.7
61
55.6
N.A.
34.9
N.A.
24
35.1
Protein Similarity:
100
87.1
N.A.
95.6
N.A.
88.3
87.8
N.A.
64.8
81.2
77.9
72.7
N.A.
54.3
N.A.
42.9
46.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
86.6
73.3
73.3
N.A.
53.3
N.A.
0
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
93.3
80
86.6
N.A.
66.6
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
24.9
N.A.
24.9
20.6
N.A.
Protein Similarity:
N.A.
38.6
N.A.
39.5
43
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
14
0
0
0
7
0
7
0
7
0
0
0
% D
% Glu:
0
0
0
54
7
0
0
0
14
7
0
0
60
74
0
% E
% Phe:
7
7
7
0
0
0
7
20
0
7
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
7
% G
% His:
0
0
7
0
7
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
54
0
14
0
0
7
0
0
7
0
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
7
0
0
0
0
0
7
7
7
% N
% Pro:
0
7
0
0
0
7
0
7
14
54
0
7
7
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% R
% Ser:
7
0
0
7
7
7
0
0
40
14
14
7
0
0
14
% S
% Thr:
7
7
7
0
54
67
60
7
7
7
14
54
0
7
60
% T
% Val:
7
0
0
7
0
0
7
7
0
0
0
7
7
0
7
% V
% Trp:
7
67
14
7
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
47
7
0
7
7
40
0
7
60
0
14
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _