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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC2L
All Species:
30.61
Human Site:
Y460
Identified Species:
48.1
UniProt:
Q13416
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13416
NP_006181.1
577
65972
Y460
P
Y
T
E
E
T
S
Y
E
N
S
L
L
V
K
Chimpanzee
Pan troglodytes
XP_516023
646
73228
Y529
P
Y
T
E
E
T
S
Y
E
N
S
L
L
V
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536028
577
66097
Y460
P
Y
T
E
E
T
S
Y
E
N
S
L
L
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60862
576
65875
Y459
P
Y
T
E
E
T
S
Y
E
N
S
L
L
V
K
Rat
Rattus norvegicus
Q75PQ8
576
65831
Y458
P
Y
T
E
E
T
S
Y
E
N
S
L
L
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520674
406
46742
L292
E
T
S
Y
E
N
S
L
L
V
Q
H
S
G
A
Chicken
Gallus gallus
NP_001006517
569
64216
Y452
P
Y
V
E
E
T
S
Y
E
N
S
L
L
V
Q
Frog
Xenopus laevis
Q91628
558
62908
Y441
S
Y
I
E
E
T
S
Y
E
N
S
L
L
V
K
Zebra Danio
Brachydanio rerio
NP_001070772
553
62538
Y437
S
Y
T
E
E
T
S
Y
E
N
S
L
L
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24168
618
68977
F502
P
Y
T
N
E
T
A
F
E
N
S
L
L
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21037
430
49301
D316
D
S
R
L
L
G
L
D
A
R
S
N
Q
S
S
Sea Urchin
Strong. purpuratus
XP_789987
337
38784
E223
Y
T
D
E
T
S
Y
E
N
S
L
L
V
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105071
377
42494
E263
T
F
A
P
Y
K
V
E
G
V
F
Y
P
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38899
363
40793
G249
F
A
P
Y
N
V
E
G
V
F
F
P
L
V
L
Baker's Yeast
Sacchar. cerevisiae
P32833
620
71220
F492
P
S
T
V
E
S
T
F
Q
D
V
M
K
M
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
N.A.
91.6
N.A.
78.8
78.6
N.A.
55.9
66.7
61
55.6
N.A.
34.9
N.A.
24
35.1
Protein Similarity:
100
87.1
N.A.
95.6
N.A.
88.3
87.8
N.A.
64.8
81.2
77.9
72.7
N.A.
54.3
N.A.
42.9
46.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
86.6
86.6
86.6
N.A.
73.3
N.A.
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
93.3
86.6
93.3
N.A.
93.3
N.A.
6.6
40
Percent
Protein Identity:
N.A.
24.9
N.A.
24.9
20.6
N.A.
Protein Similarity:
N.A.
38.6
N.A.
39.5
43
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
7
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
0
7
0
7
0
0
0
0
0
% D
% Glu:
7
0
0
60
74
0
7
14
60
0
0
0
0
0
0
% E
% Phe:
7
7
0
0
0
0
0
14
0
7
14
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
7
7
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
40
% K
% Leu:
0
0
0
7
7
0
7
7
7
0
7
67
67
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% M
% Asn:
0
0
0
7
7
7
0
0
7
60
0
7
0
0
0
% N
% Pro:
54
0
7
7
0
0
0
0
0
0
0
7
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
7
0
7
7
27
% Q
% Arg:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
14
14
7
0
0
14
60
0
0
7
67
0
7
7
7
% S
% Thr:
7
14
54
0
7
60
7
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
7
0
7
7
0
7
14
7
0
7
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
60
0
14
7
0
7
54
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _