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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC2L
All Species:
26.36
Human Site:
Y498
Identified Species:
41.43
UniProt:
Q13416
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13416
NP_006181.1
577
65972
Y498
I
F
R
L
L
I
K
Y
Q
L
D
N
Q
D
N
Chimpanzee
Pan troglodytes
XP_516023
646
73228
Y567
I
F
R
L
L
I
K
Y
Q
L
D
N
Q
D
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536028
577
66097
Y498
I
F
R
L
L
I
K
Y
Q
L
D
N
L
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q60862
576
65875
F497
I
F
R
L
L
M
K
F
Q
L
D
N
Q
D
S
Rat
Rattus norvegicus
Q75PQ8
576
65831
Y496
I
F
R
L
L
M
K
Y
Q
L
D
N
Q
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520674
406
46742
N330
L
T
K
Y
Q
L
E
N
K
D
N
P
S
Y
I
Chicken
Gallus gallus
NP_001006517
569
64216
Y490
I
F
R
L
L
A
Q
Y
Q
L
E
N
K
D
N
Frog
Xenopus laevis
Q91628
558
62908
Y479
I
F
R
L
L
A
E
Y
Q
M
A
N
K
D
N
Zebra Danio
Brachydanio rerio
NP_001070772
553
62538
F475
I
F
R
L
L
A
E
F
Q
L
E
N
K
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24168
618
68977
Y540
I
Y
M
L
I
V
K
Y
Q
L
K
N
K
G
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21037
430
49301
T354
F
F
Q
M
Y
F
D
T
K
K
P
V
K
F
W
Sea Urchin
Strong. purpuratus
XP_789987
337
38784
Q261
F
N
I
L
V
E
F
Q
M
E
H
K
D
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105071
377
42494
L301
A
Q
S
V
F
R
V
L
A
E
Y
Q
L
A
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38899
363
40793
A287
Q
N
V
F
K
I
L
A
E
Y
Q
L
S
H
P
Baker's Yeast
Sacchar. cerevisiae
P32833
620
71220
E530
K
M
Y
K
L
L
I
E
T
Q
M
Q
N
M
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
N.A.
91.6
N.A.
78.8
78.6
N.A.
55.9
66.7
61
55.6
N.A.
34.9
N.A.
24
35.1
Protein Similarity:
100
87.1
N.A.
95.6
N.A.
88.3
87.8
N.A.
64.8
81.2
77.9
72.7
N.A.
54.3
N.A.
42.9
46.9
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
86.6
N.A.
0
73.3
66.6
66.6
N.A.
53.3
N.A.
6.6
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
40
93.3
86.6
93.3
N.A.
80
N.A.
33.3
20
Percent
Protein Identity:
N.A.
24.9
N.A.
24.9
20.6
N.A.
Protein Similarity:
N.A.
38.6
N.A.
39.5
43
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
20
0
7
7
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
7
0
0
7
34
0
7
60
0
% D
% Glu:
0
0
0
0
0
7
20
7
7
14
14
0
0
0
0
% E
% Phe:
14
60
0
7
7
7
7
14
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
60
0
7
0
7
27
7
0
0
0
0
0
0
0
7
% I
% Lys:
7
0
7
7
7
0
40
0
14
7
7
7
34
0
0
% K
% Leu:
7
0
0
67
60
14
7
7
0
54
0
7
14
0
0
% L
% Met:
0
7
7
7
0
14
0
0
7
7
7
0
0
7
0
% M
% Asn:
0
14
0
0
0
0
0
7
0
0
7
60
7
0
54
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
7
% P
% Gln:
7
7
7
0
7
0
7
7
60
7
7
14
27
0
0
% Q
% Arg:
0
0
54
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
0
0
14
0
7
% S
% Thr:
0
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% T
% Val:
0
0
7
7
7
7
7
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
7
7
7
7
0
0
47
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _