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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ILK
All Species:
45.45
Human Site:
S377
Identified Species:
83.33
UniProt:
Q13418
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13418
NP_001014794.1
452
51419
S377
R
R
S
A
D
M
W
S
F
A
V
L
L
W
E
Chimpanzee
Pan troglodytes
XP_001164277
401
45629
I349
A
D
L
S
N
M
E
I
G
M
K
V
A
L
E
Rhesus Macaque
Macaca mulatta
XP_001108844
482
54677
S407
R
R
S
A
D
M
W
S
F
A
V
L
L
W
E
Dog
Lupus familis
XP_534040
452
51371
S377
R
R
S
A
D
M
W
S
F
A
V
L
L
W
E
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q99J82
452
51355
S377
R
R
S
A
D
M
W
S
F
A
V
L
L
W
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09324
541
60774
S455
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
Frog
Xenopus laevis
NP_001086805
452
51540
S377
R
R
S
A
D
M
W
S
F
A
V
L
L
W
E
Zebra Danio
Brachydanio rerio
NP_956865
452
51045
S377
R
R
S
A
D
M
W
S
Y
A
V
L
L
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525001
448
50724
S374
W
E
A
C
D
M
W
S
F
A
I
L
I
W
E
Honey Bee
Apis mellifera
XP_396799
449
50561
S375
L
E
A
S
D
M
W
S
F
A
V
L
L
W
E
Nematode Worm
Caenorhab. elegans
NP_497139
466
52241
S392
I
R
A
A
D
M
W
S
F
A
I
L
L
W
E
Sea Urchin
Strong. purpuratus
XP_786444
448
50461
S373
A
R
S
A
D
M
W
S
F
A
I
L
I
W
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001152374
534
58727
S440
D
S
K
A
D
V
Y
S
F
A
L
V
L
W
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
93.7
99.7
N.A.
N.A.
99.5
N.A.
N.A.
23.4
88.9
86.7
N.A.
60.1
61.5
56.4
59.5
Protein Similarity:
100
88.7
93.7
99.7
N.A.
N.A.
99.7
N.A.
N.A.
39.9
94.6
93.3
N.A.
75.4
77.2
75.5
79.4
P-Site Identity:
100
13.3
100
100
N.A.
N.A.
100
N.A.
N.A.
46.6
100
93.3
N.A.
60
73.3
80
80
P-Site Similarity:
100
33.3
100
100
N.A.
N.A.
100
N.A.
N.A.
66.6
100
100
N.A.
80
86.6
93.3
93.3
Percent
Protein Identity:
N.A.
24.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
44.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
80
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
24
70
0
0
0
0
0
85
0
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
93
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
85
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
0
31
0
16
0
0
% I
% Lys:
0
0
16
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
0
0
0
0
8
85
77
8
0
% L
% Met:
0
0
0
0
0
85
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
47
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
54
24
0
0
0
93
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
16
0
0
0
0
54
16
0
0
0
% V
% Trp:
8
0
0
0
0
0
85
0
0
0
0
0
0
85
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _