Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILK All Species: 15.15
Human Site: T266 Identified Species: 27.78
UniProt: Q13418 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13418 NP_001014794.1 452 51419 T266 S P P A P H P T L I T H W M P
Chimpanzee Pan troglodytes XP_001164277 401 45629 Q242 N F V V D Q S Q A V K F A L D
Rhesus Macaque Macaca mulatta XP_001108844 482 54677 T296 S P P A P H P T L I T H W M P
Dog Lupus familis XP_534040 452 51371 T266 S P P A P H P T L I T H W M P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q99J82 452 51355 T266 A P P A P H P T L I T H W M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09324 541 60774 Y343 V V S E E P I Y I V T E F M T
Frog Xenopus laevis NP_001086805 452 51540 V266 S P P A P H P V L I T H W M P
Zebra Danio Brachydanio rerio NP_956865 452 51045 I266 S P P A P H P I I I T H S M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525001 448 50724 I265 S P P N L V T I S Q F M P R S
Honey Bee Apis mellifera XP_396799 449 50561 V265 Q P P K L A T V S Q Y M A R G
Nematode Worm Caenorhab. elegans NP_497139 466 52241 V281 A N Q P P N L V I I S Q Y M P
Sea Urchin Strong. purpuratus XP_786444 448 50461 L264 Q P P N L V V L S E T L Q H G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001152374 534 58727 F330 S C T K P P Q F Y I I T E C M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 93.7 99.7 N.A. N.A. 99.5 N.A. N.A. 23.4 88.9 86.7 N.A. 60.1 61.5 56.4 59.5
Protein Similarity: 100 88.7 93.7 99.7 N.A. N.A. 99.7 N.A. N.A. 39.9 94.6 93.3 N.A. 75.4 77.2 75.5 79.4
P-Site Identity: 100 0 100 100 N.A. N.A. 93.3 N.A. N.A. 13.3 93.3 80 N.A. 20 13.3 26.6 20
P-Site Similarity: 100 20 100 100 N.A. N.A. 100 N.A. N.A. 33.3 93.3 86.6 N.A. 20 13.3 60 20
Percent
Protein Identity: N.A. 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 44.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 20 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 47 0 8 0 0 8 0 0 0 16 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 8 8 0 0 0 0 8 0 8 8 0 0 % E
% Phe: 0 8 0 0 0 0 0 8 0 0 8 8 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % G
% His: 0 0 0 0 0 47 0 0 0 0 0 47 0 8 0 % H
% Ile: 0 0 0 0 0 0 8 16 24 62 8 0 0 0 0 % I
% Lys: 0 0 0 16 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 0 24 0 8 8 39 0 0 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 16 0 62 8 % M
% Asn: 8 8 0 16 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 70 70 8 62 16 47 0 0 0 0 0 8 0 54 % P
% Gln: 16 0 8 0 0 8 8 8 0 16 0 8 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % R
% Ser: 54 0 8 0 0 0 8 0 24 0 8 0 8 0 8 % S
% Thr: 0 0 8 0 0 0 16 31 0 0 62 8 0 0 8 % T
% Val: 8 8 8 8 0 16 8 24 0 16 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 8 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _