KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKZF1
All Species:
3.64
Human Site:
S49
Identified Species:
8.89
UniProt:
Q13422
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13422
NP_006051.1
519
57528
S49
G
G
Q
Q
S
S
K
S
D
R
V
V
A
S
N
Chimpanzee
Pan troglodytes
XP_001148911
633
70244
P163
R
D
F
H
A
I
I
P
K
S
F
S
P
S
N
Rhesus Macaque
Macaca mulatta
XP_001082512
448
50212
R11
E
E
C
A
E
D
L
R
M
L
D
A
S
G
E
Dog
Lupus familis
XP_540350
579
63964
N89
G
G
Q
Q
T
S
K
N
E
R
G
V
V
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q03267
517
57318
S49
G
A
Q
Q
N
S
K
S
D
R
G
M
G
S
N
Rat
Rattus norvegicus
NP_001100707
428
47918
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506295
728
80167
N259
G
G
Q
Q
N
S
K
N
E
R
V
L
A
G
N
Chicken
Gallus gallus
O42410
518
57568
N49
G
G
Q
Q
S
V
K
N
E
R
V
L
A
G
N
Frog
Xenopus laevis
Q6NRM0
453
49949
Q16
L
D
F
V
K
D
F
Q
E
Y
L
T
Q
Q
T
Zebra Danio
Brachydanio rerio
Q6DBW0
419
46136
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
84.7
80.6
N.A.
92
76.8
N.A.
63.4
85.9
22.3
24.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.4
85.1
84.8
N.A.
95.5
79.5
N.A.
67.8
93.6
40.6
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
53.3
N.A.
66.6
0
N.A.
66.6
66.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
73.3
N.A.
80
0
N.A.
93.3
86.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
0
0
0
0
0
0
10
30
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
20
0
0
20
0
10
0
0
0
0
% D
% Glu:
10
10
0
0
10
0
0
0
40
0
0
0
0
0
10
% E
% Phe:
0
0
20
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
50
40
0
0
0
0
0
0
0
0
20
0
10
30
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
50
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
10
0
0
10
10
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
30
0
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% P
% Gln:
0
0
50
50
0
0
0
10
0
0
0
0
10
10
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
50
0
0
0
0
0
% R
% Ser:
0
0
0
0
20
40
0
20
0
10
0
10
10
30
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% T
% Val:
0
0
0
10
0
10
0
0
0
0
30
20
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _