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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NNT All Species: 19.7
Human Site: Y551 Identified Species: 48.15
UniProt: Q13423 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13423 NP_036475.3 1086 113896 Y551 A L M G G H L Y P S T T S Q G
Chimpanzee Pan troglodytes XP_001134902 1086 113819 Y551 A L M G G H L Y P S T T S Q G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536481 1086 113623 Y551 A L M G G H L Y P S T T S Q G
Cat Felis silvestris
Mouse Mus musculus Q61941 1086 113820 Y551 A L M G G H F Y P S T T S Q S
Rat Rattus norvegicus NP_001013175 1086 113851 Y551 A L M G G H F Y P S T T S Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508040 959 99995 S454 G A P V K Q K S V A E L E A E
Chicken Gallus gallus
Frog Xenopus laevis NP_001087704 1086 113982 L551 A L M G G G Y L P T N T H E L
Zebra Danio Brachydanio rerio NP_999921 1079 112765 L547 S L M G G G Y L P S S T A E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_509028 1041 109661 T532 I G G G F L V T K R M L D M F
Sea Urchin Strong. purpuratus NP_001116985 1071 113445 Y535 V C M S G G Y Y P D S T P A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 96.5 N.A. 93 93 N.A. 79.7 N.A. 86.7 82.3 N.A. N.A. N.A. 60.1 65.1
Protein Similarity: 100 99.8 N.A. 98.4 N.A. 96.2 96 N.A. 84 N.A. 94.1 91.1 N.A. N.A. N.A. 73.3 78.8
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 0 N.A. 46.6 46.6 N.A. N.A. N.A. 6.6 33.3
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 6.6 N.A. 60 73.3 N.A. N.A. N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 10 0 0 0 0 0 0 0 10 0 0 10 20 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 10 20 10 % E
% Phe: 0 0 0 0 10 0 20 0 0 0 0 0 0 0 10 % F
% Gly: 10 10 10 80 80 30 0 0 0 0 0 0 0 0 30 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 0 % K
% Leu: 0 70 0 0 0 10 30 20 0 0 0 20 0 0 10 % L
% Met: 0 0 80 0 0 0 0 0 0 0 10 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 80 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 50 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 10 0 0 10 0 0 0 10 0 60 20 0 50 0 20 % S
% Thr: 0 0 0 0 0 0 0 10 0 10 50 80 0 0 20 % T
% Val: 10 0 0 10 0 0 10 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 30 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _