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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC4
All Species:
5.76
Human Site:
T241
Identified Species:
14.07
UniProt:
Q13426
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13426
NP_003392.1
336
38287
T241
D
E
E
S
E
N
Q
T
D
L
S
G
L
A
S
Chimpanzee
Pan troglodytes
XP_001148110
336
38223
T241
D
E
E
S
E
N
Q
T
D
P
S
G
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001111757
336
38393
P241
D
E
E
N
E
N
Q
P
D
P
S
G
S
A
S
Dog
Lupus familis
XP_849518
335
38080
P240
D
E
E
K
E
K
L
P
N
P
S
V
S
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q924T3
326
37042
E234
Y
D
G
S
T
D
E
E
S
G
A
P
V
Q
A
Rat
Rattus norvegicus
NP_001007000
323
36459
G226
E
E
D
G
L
Y
D
G
S
T
D
E
E
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424905
234
26756
Q142
L
D
C
L
G
G
L
Q
V
K
N
E
H
L
Q
Frog
Xenopus laevis
NP_001085360
362
40705
S269
C
I
N
A
C
P
S
S
G
L
V
S
K
S
N
Zebra Danio
Brachydanio rerio
NP_957080
357
40801
P262
E
D
E
Q
E
A
E
P
K
R
L
D
P
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181652
239
26963
E147
S
I
Y
R
L
E
S
E
N
D
R
L
S
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
79.1
N.A.
73.8
70.5
N.A.
N.A.
42.8
44.2
38
N.A.
N.A.
N.A.
N.A.
20.2
Protein Similarity:
100
99.4
97
85.4
N.A.
80.6
77.9
N.A.
N.A.
51.7
59.3
55.4
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
93.3
73.3
40
N.A.
6.6
6.6
N.A.
N.A.
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
80
46.6
N.A.
46.6
26.6
N.A.
N.A.
13.3
33.3
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
10
0
0
40
10
% A
% Cys:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
30
10
0
0
10
10
0
30
10
10
10
0
0
0
% D
% Glu:
20
50
50
0
50
10
20
20
0
0
0
20
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
10
10
0
10
10
10
0
30
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
10
0
0
10
10
0
0
10
10
0
% K
% Leu:
10
0
0
10
20
0
20
0
0
20
10
10
20
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
30
0
0
20
0
10
0
0
10
10
% N
% Pro:
0
0
0
0
0
10
0
30
0
30
0
10
10
0
20
% P
% Gln:
0
0
0
10
0
0
30
10
0
0
0
0
0
10
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
10
0
0
30
0
0
20
10
20
0
40
10
30
20
30
% S
% Thr:
0
0
0
0
10
0
0
20
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _