Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIG All Species: 33.33
Human Site: S194 Identified Species: 56.41
UniProt: Q13427 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13427 NP_004783.2 754 88617 S194 E K K R H K S S S S S S S S S
Chimpanzee Pan troglodytes XP_001136305 754 88627 S194 E K K R H K S S S S S S S S S
Rhesus Macaque Macaca mulatta XP_001104730 754 88634 S194 E K K R H K S S S S S S S S S
Dog Lupus familis XP_849611 753 88672 S194 E K K R H K S S S S S S S S S
Cat Felis silvestris
Mouse Mus musculus A2AR02 752 88306 S194 E K K R H K S S S S S S S S D
Rat Rattus norvegicus O55035 752 88360 S194 E K K R H K S S S S S S S S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514716 753 88278 S194 E K K R H K S S S S S S D S E
Chicken Gallus gallus XP_422008 750 88100 S194 D K K R H K S S S S S S D S E
Frog Xenopus laevis NP_001089456 247 27734
Zebra Danio Brachydanio rerio XP_001338072 1394 158189 F193 Q G K L R K A F Y S E D D S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733246 970 112777 T199 K K H K R R S T A T E D S N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52016 466 53547
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53691 371 42053
Red Bread Mold Neurospora crassa Q9P3X9 375 40552
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.6 N.A. 93.2 93.2 N.A. 82.8 76.6 28.9 26 N.A. 31.1 N.A. 30.2 N.A.
Protein Similarity: 100 100 99.4 98 N.A. 96.5 96.8 N.A. 91.1 88 31.4 39 N.A. 46.7 N.A. 43 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 80 0 26.6 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 86.6 0 40 N.A. 73.3 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.2 25.6
Protein Similarity: N.A. N.A. N.A. N.A. 33.9 36
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 15 22 0 15 % D
% Glu: 50 0 0 0 0 0 0 0 0 0 15 0 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 58 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 65 65 8 0 65 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 58 15 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 65 58 58 65 58 58 50 65 36 % S
% Thr: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _