KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIG
All Species:
26.06
Human Site:
S460
Identified Species:
44.1
UniProt:
Q13427
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13427
NP_004783.2
754
88617
S460
K
K
R
A
K
S
K
S
R
S
K
S
K
E
K
Chimpanzee
Pan troglodytes
XP_001136305
754
88627
S460
K
K
R
A
K
S
K
S
R
S
K
S
K
E
K
Rhesus Macaque
Macaca mulatta
XP_001104730
754
88634
S460
K
K
R
A
K
S
K
S
R
S
K
S
K
E
K
Dog
Lupus familis
XP_849611
753
88672
K460
V
K
K
R
A
K
S
K
S
R
S
K
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
A2AR02
752
88306
S459
K
K
R
G
K
S
K
S
R
S
K
S
K
E
R
Rat
Rattus norvegicus
O55035
752
88360
S459
K
K
R
G
K
S
K
S
R
S
K
S
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514716
753
88278
S459
K
K
R
G
K
S
K
S
R
S
K
S
K
E
K
Chicken
Gallus gallus
XP_422008
750
88100
S455
K
T
K
K
R
G
K
S
R
S
H
S
K
S
R
Frog
Xenopus laevis
NP_001089456
247
27734
Zebra Danio
Brachydanio rerio
XP_001338072
1394
158189
L799
Q
K
N
T
L
D
S
L
S
A
L
R
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733246
970
112777
K530
T
E
E
K
A
K
P
K
R
S
R
S
R
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52016
466
53547
V177
I
T
H
C
G
E
M
V
R
K
G
D
V
V
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53691
371
42053
T82
D
F
T
N
F
N
G
T
G
G
E
S
I
Y
D
Red Bread Mold
Neurospora crassa
Q9P3X9
375
40552
N86
G
G
D
F
T
A
G
N
G
T
G
G
E
S
I
Conservation
Percent
Protein Identity:
100
99.8
98.9
95.6
N.A.
93.2
93.2
N.A.
82.8
76.6
28.9
26
N.A.
31.1
N.A.
30.2
N.A.
Protein Similarity:
100
100
99.4
98
N.A.
96.5
96.8
N.A.
91.1
88
31.4
39
N.A.
46.7
N.A.
43
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
93.3
46.6
0
6.6
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
93.3
66.6
0
20
N.A.
40
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
25.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.9
36
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
15
8
0
0
0
8
0
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
8
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
8
8
0
0
8
0
0
0
0
8
0
8
43
8
% E
% Phe:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
22
8
8
15
0
15
8
15
8
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
50
58
15
15
43
15
50
15
0
8
43
8
50
8
29
% K
% Leu:
0
0
0
0
8
0
0
8
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
43
8
8
0
0
0
65
8
8
8
8
0
22
% R
% Ser:
0
0
0
0
0
43
15
50
15
58
8
65
8
22
0
% S
% Thr:
8
15
8
8
8
0
0
8
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _