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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIG All Species: 24.55
Human Site: S572 Identified Species: 41.54
UniProt: Q13427 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13427 NP_004783.2 754 88617 S572 R S R S R D R S R R V R S R T
Chimpanzee Pan troglodytes XP_001136305 754 88627 S572 R S R S R D R S R R V R S R T
Rhesus Macaque Macaca mulatta XP_001104730 754 88634 S572 R S R S R D R S R R V R S R T
Dog Lupus familis XP_849611 753 88672 S572 R S R S R D R S R R V R S R S
Cat Felis silvestris
Mouse Mus musculus A2AR02 752 88306 S571 R S R S R D R S R R V R S R S
Rat Rattus norvegicus O55035 752 88360 S571 R S R S R D R S R R V R S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514716 753 88278 G571 R S R S R D R G R R G R S R S
Chicken Gallus gallus XP_422008 750 88100 G567 R S K S R D R G R R G R S R S
Frog Xenopus laevis NP_001089456 247 27734 K70 C L F H R V V K D F M I Q G G
Zebra Danio Brachydanio rerio XP_001338072 1394 158189 A911 P L W P N L G A E M S K E L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733246 970 112777 S642 P S Q R R Q L S P G R K R Q D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52016 466 53547 D289 S G R D E R R D D R R S S A P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53691 371 42053 G194 A T P T D E Y G D N Y E D V L
Red Bread Mold Neurospora crassa Q9P3X9 375 40552 E198 T A D A Y G D E Y E D F P E D
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.6 N.A. 93.2 93.2 N.A. 82.8 76.6 28.9 26 N.A. 31.1 N.A. 30.2 N.A.
Protein Similarity: 100 100 99.4 98 N.A. 96.5 96.8 N.A. 91.1 88 31.4 39 N.A. 46.7 N.A. 43 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 80 73.3 6.6 0 N.A. 20 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 86.6 13.3 13.3 N.A. 40 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.2 25.6
Protein Similarity: N.A. N.A. N.A. N.A. 33.9 36
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 0 0 8 0 0 0 0 0 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 8 58 8 8 22 0 8 0 8 0 15 % D
% Glu: 0 0 0 0 8 8 0 8 8 8 0 8 8 8 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 8 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 8 8 22 0 8 15 0 0 8 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 8 0 0 0 15 0 0 8 % K
% Leu: 0 15 0 0 0 8 8 0 0 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 15 0 8 8 0 0 0 0 8 0 0 0 8 0 8 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 0 0 8 8 0 % Q
% Arg: 58 0 58 8 72 8 65 0 58 65 15 58 8 58 0 % R
% Ser: 8 65 0 58 0 0 0 50 0 0 8 8 65 0 36 % S
% Thr: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 22 % T
% Val: 0 0 0 0 0 8 8 0 0 0 43 0 0 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 8 0 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _