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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIG All Species: 33.03
Human Site: S745 Identified Species: 55.9
UniProt: Q13427 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13427 NP_004783.2 754 88617 S745 K K F D H E S S P G T D E D K
Chimpanzee Pan troglodytes XP_001136305 754 88627 S745 K K F D H E S S P G T D E D K
Rhesus Macaque Macaca mulatta XP_001104730 754 88634 S745 K K F D H E S S P G T D E D K
Dog Lupus familis XP_849611 753 88672 S744 K K F D H E S S P G T D E D K
Cat Felis silvestris
Mouse Mus musculus A2AR02 752 88306 S743 K K C D H E S S P G T D E D K
Rat Rattus norvegicus O55035 752 88360 S743 K K C D H E S S P G T D E D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514716 753 88278 S744 K K S D H E S S P G T D E G K
Chicken Gallus gallus XP_422008 750 88100 S741 K K S D R E T S P G T D D D R
Frog Xenopus laevis NP_001089456 247 27734 K239 K Q K K E K R K S K K N K E K
Zebra Danio Brachydanio rerio XP_001338072 1394 158189 S1364 R R R G H R R S K S S D R R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733246 970 112777 Q885 R R M E K Q R Q D D L D K E R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52016 466 53547 S458 S S S S S S S S S G H S S D S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53691 371 42053 K363 K Q Q N E K A K K S L S K M F
Red Bread Mold Neurospora crassa Q9P3X9 375 40552 K367 A A R M A K E K A A Y K K F F
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.6 N.A. 93.2 93.2 N.A. 82.8 76.6 28.9 26 N.A. 31.1 N.A. 30.2 N.A.
Protein Similarity: 100 100 99.4 98 N.A. 96.5 96.8 N.A. 91.1 88 31.4 39 N.A. 46.7 N.A. 43 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 66.6 13.3 20 N.A. 6.6 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 86.6 46.6 40 N.A. 53.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.2 25.6
Protein Similarity: N.A. N.A. N.A. N.A. 33.9 36
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 8 0 8 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 58 0 0 0 0 8 8 0 72 8 58 0 % D
% Glu: 0 0 0 8 15 58 8 0 0 0 0 0 50 15 0 % E
% Phe: 0 0 29 0 0 0 0 0 0 0 0 0 0 8 15 % F
% Gly: 0 0 0 8 0 0 0 0 0 65 0 0 0 8 0 % G
% His: 0 0 0 0 58 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 72 58 8 8 8 22 0 22 15 8 8 8 29 0 58 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 % P
% Gln: 0 15 8 0 0 8 0 8 0 0 0 0 0 0 0 % Q
% Arg: 15 15 15 0 8 8 22 0 0 0 0 0 8 8 15 % R
% Ser: 8 8 22 8 8 8 58 72 15 15 8 15 8 0 15 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 58 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _