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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED1
All Species:
30.91
Human Site:
S168
Identified Species:
75.56
UniProt:
Q13445
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13445
NP_006849.1
227
25206
S168
M
R
T
R
L
E
R
S
I
Q
M
L
T
L
L
Chimpanzee
Pan troglodytes
XP_512383
226
25056
S167
M
R
T
R
L
E
R
S
I
Q
M
L
T
L
L
Rhesus Macaque
Macaca mulatta
XP_001103770
227
25115
S168
M
R
T
R
L
E
R
S
I
Q
M
L
T
L
L
Dog
Lupus familis
XP_542064
226
25028
S167
M
K
T
R
L
E
R
S
I
Q
M
L
T
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3V009
227
25244
S168
M
R
T
R
L
E
R
S
I
Q
M
L
T
L
L
Rat
Rattus norvegicus
Q5BK85
227
25191
S168
M
R
T
R
L
E
R
S
I
Q
M
L
T
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516847
317
34862
S154
M
K
T
R
L
E
R
S
I
Q
V
L
T
L
L
Chicken
Gallus gallus
NP_001007957
226
25656
S167
V
K
A
R
L
S
K
S
V
Q
I
Q
T
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572994
242
27783
A176
I
R
L
Q
L
T
K
A
R
Q
L
Q
D
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
I156
I
D
R
N
L
N
K
I
T
K
T
L
N
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
96.9
N.A.
95.1
94.7
N.A.
47.9
55.5
N.A.
N.A.
N.A.
35.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.5
98.6
N.A.
96.9
96.4
N.A.
54.5
71.3
N.A.
N.A.
N.A.
55.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
46.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
80
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
0
10
70
0
10
0
0
0
0
% I
% Lys:
0
30
0
0
0
0
30
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
10
0
100
0
0
0
0
0
10
80
0
80
100
% L
% Met:
70
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
90
0
20
0
0
0
% Q
% Arg:
0
60
10
80
0
0
70
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
80
0
0
0
0
0
0
0
% S
% Thr:
0
0
70
0
0
10
0
0
10
0
10
0
80
0
0
% T
% Val:
10
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _