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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP5 All Species: 26.06
Human Site: S160 Identified Species: 40.95
UniProt: Q13451 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13451 NP_001139247.1 457 51212 S160 K R K G E G Y S N P N E G A T
Chimpanzee Pan troglodytes XP_001172411 457 51122 S160 K R K G E G Y S N P N E G A T
Rhesus Macaque Macaca mulatta XP_001098079 459 51670 A162 R T R G E G Y A K P N E G A I
Dog Lupus familis XP_538880 456 51014 S160 K Q K G E G Y S N P N E G A T
Cat Felis silvestris
Mouse Mus musculus Q64378 456 50948 S160 K R K G E G Y S N P N E G A T
Rat Rattus norvegicus Q9QVC8 458 51432 A162 R T R G E G Y A R P N D G A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512517 419 46551 R146 L E G C C S G R T F D C R D V
Chicken Gallus gallus NP_001005431 449 50409 S160 K R K G E G Y S N P N E G A T
Frog Xenopus laevis NP_001084593 447 50080 S158 R V K G E G Y S K P N E G A V
Zebra Danio Brachydanio rerio NP_998314 453 51464 S160 K V K G E G Y S N P N E G A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 I156 G A F V K A H I S G S F E G R
Honey Bee Apis mellifera XP_395748 459 51510 G161 H L M G M Y N G K I F E D R D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781282 422 47590 D169 V T E G Q E Y D T P N D E A K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141458 458 51432 A162 R T R G E G Y A R P N D G A M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 E168 L A V G E K W E N P K D L D E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 54 95.1 N.A. 87 53.7 N.A. 69.8 83.1 55.5 58.6 N.A. 39.3 47 N.A. 44.2
Protein Similarity: 100 99.7 73.8 96.7 N.A. 91.6 72.4 N.A. 77.6 88.8 70.9 75.2 N.A. 56.6 61.2 N.A. 62.8
P-Site Identity: 100 100 60 93.3 N.A. 100 53.3 N.A. 0 100 73.3 93.3 N.A. 0 13.3 N.A. 33.3
P-Site Similarity: 100 100 80 100 N.A. 100 80 N.A. 6.6 100 80 93.3 N.A. 26.6 13.3 N.A. 53.3
Percent
Protein Identity: N.A. 53.7 N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. 72.4 N.A. 47 N.A. N.A.
P-Site Identity: N.A. 53.3 N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. 80 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 7 0 20 0 0 0 0 0 74 0 % A
% Cys: 0 0 0 7 7 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 7 27 7 14 7 % D
% Glu: 0 7 7 0 74 7 0 7 0 0 0 60 14 0 7 % E
% Phe: 0 0 7 0 0 0 0 0 0 7 7 7 0 0 0 % F
% Gly: 7 0 7 87 0 67 7 7 0 7 0 0 67 7 0 % G
% His: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 7 % I
% Lys: 40 0 47 0 7 7 0 0 20 0 7 0 0 0 7 % K
% Leu: 14 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % L
% Met: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 14 % M
% Asn: 0 0 0 0 0 0 7 0 47 0 74 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 27 27 20 0 0 0 0 7 14 0 0 0 7 7 7 % R
% Ser: 0 0 0 0 0 7 0 47 7 0 7 0 0 0 0 % S
% Thr: 0 27 0 0 0 0 0 0 14 0 0 0 0 0 40 % T
% Val: 7 14 7 7 0 0 0 0 0 0 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 74 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _