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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
15.15
Human Site:
S27
Identified Species:
23.81
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
S27
E
Q
G
E
D
I
T
S
K
K
D
R
G
V
L
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
S27
E
Q
G
E
D
I
T
S
K
K
D
R
G
V
L
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
P27
I
E
G
V
D
I
S
P
K
Q
D
E
G
V
L
Dog
Lupus familis
XP_538880
456
51014
S27
E
R
G
E
D
I
T
S
K
K
D
R
G
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
T27
E
Q
G
E
D
I
T
T
K
K
D
R
G
V
L
Rat
Rattus norvegicus
Q9QVC8
458
51432
P27
L
E
G
V
D
I
S
P
K
Q
D
E
G
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
K27
G
S
L
S
D
G
G
K
V
Y
V
P
L
P
Q
Chicken
Gallus gallus
NP_001005431
449
50409
P27
E
R
G
E
D
I
T
P
T
R
D
R
G
V
L
Frog
Xenopus laevis
NP_001084593
447
50080
Q27
D
I
T
P
K
G
D
Q
G
V
L
K
L
I
K
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
P27
S
R
G
T
A
V
T
P
N
G
D
S
G
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
T28
K
E
G
T
G
T
E
T
P
H
S
G
C
T
V
Honey Bee
Apis mellifera
XP_395748
459
51510
I27
K
E
G
I
G
D
E
I
P
S
P
G
S
N
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
P33
G
T
G
Q
D
V
T
P
N
G
D
G
G
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
P27
L
E
G
V
D
I
S
P
K
Q
D
E
G
V
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
E33
S
F
L
K
V
G
E
E
K
E
I
Q
Q
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
100
53.3
93.3
N.A.
93.3
53.3
N.A.
6.6
73.3
0
33.3
N.A.
6.6
6.6
N.A.
46.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
73.3
N.A.
6.6
86.6
20
46.6
N.A.
33.3
26.6
N.A.
60
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
7
0
0
0
67
7
7
0
0
0
67
0
0
0
0
% D
% Glu:
34
34
0
34
0
0
20
7
0
7
0
20
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
80
0
14
20
7
0
7
14
0
20
67
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
54
0
7
0
0
7
0
0
7
0
% I
% Lys:
14
0
0
7
7
0
0
7
54
27
0
7
0
0
7
% K
% Leu:
14
0
14
0
0
0
0
0
0
0
7
0
14
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
14
0
0
0
0
7
0
% N
% Pro:
0
0
0
7
0
0
0
40
14
0
7
7
0
7
0
% P
% Gln:
0
20
0
7
0
0
0
7
0
20
0
7
7
0
7
% Q
% Arg:
0
20
0
0
0
0
0
0
0
7
0
34
0
0
0
% R
% Ser:
14
7
0
7
0
0
20
20
0
7
7
7
7
0
0
% S
% Thr:
0
7
7
14
0
7
47
14
7
0
0
0
0
7
0
% T
% Val:
0
0
0
20
7
14
0
0
7
7
7
0
0
67
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _