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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
24.24
Human Site:
S309
Identified Species:
38.1
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
S309
Y
G
L
S
E
K
E
S
K
A
S
E
S
F
L
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
S309
Y
G
L
S
E
K
E
S
K
A
S
E
S
F
L
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
A311
S
S
F
S
S
E
E
A
Q
K
A
Q
A
L
R
Dog
Lupus familis
XP_538880
456
51014
S309
Y
G
L
S
E
K
E
S
K
A
S
E
S
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
S309
Y
G
L
S
E
K
E
S
K
A
S
E
S
F
L
Rat
Rattus norvegicus
Q9QVC8
458
51432
M311
S
S
F
S
G
E
E
M
Q
K
V
H
A
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
S276
Y
G
L
S
E
H
E
S
K
A
S
E
S
F
L
Chicken
Gallus gallus
NP_001005431
449
50409
S309
Y
G
L
S
E
K
E
S
K
A
S
D
S
F
L
Frog
Xenopus laevis
NP_001084593
447
50080
D307
S
G
L
S
K
E
E
D
A
K
A
K
S
L
I
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
L309
C
G
N
G
K
E
Q
L
Q
A
I
Q
A
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
N289
L
P
T
T
V
H
T
N
E
E
V
K
K
I
K
Honey Bee
Apis mellifera
XP_395748
459
51510
K291
E
D
F
E
G
D
L
K
I
E
R
N
N
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
A296
K
Q
G
R
Y
Q
D
A
I
K
Q
W
K
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
M311
S
S
F
S
G
E
E
M
Q
K
V
H
A
L
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
S360
Y
A
F
G
S
N
E
S
Q
Q
E
L
A
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
100
13.3
100
N.A.
100
13.3
N.A.
93.3
93.3
33.3
20
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
53.3
100
N.A.
100
33.3
N.A.
93.3
100
66.6
60
N.A.
26.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
14
7
47
14
0
34
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
7
7
7
0
0
0
7
0
0
0
% D
% Glu:
7
0
0
7
40
34
74
0
7
14
7
34
0
0
0
% E
% Phe:
0
0
34
0
0
0
0
0
0
0
0
0
0
40
0
% F
% Gly:
0
54
7
14
20
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
14
0
0
0
0
0
14
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
14
0
7
0
0
7
20
% I
% Lys:
7
0
0
0
14
34
0
7
40
34
0
14
14
7
7
% K
% Leu:
7
0
47
0
0
0
7
7
0
0
0
7
0
40
47
% L
% Met:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
7
0
0
0
7
7
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
7
0
34
7
7
14
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
20
% R
% Ser:
27
20
0
67
14
0
0
47
0
0
40
0
47
0
0
% S
% Thr:
0
0
7
7
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
20
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
47
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _