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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
25.45
Human Site:
S348
Identified Species:
40
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
S348
D
K
A
L
G
L
D
S
A
N
E
K
G
L
Y
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
S348
D
K
A
L
G
L
D
S
A
N
E
K
G
L
Y
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
S350
N
K
A
L
E
L
D
S
N
N
E
K
G
L
F
Dog
Lupus familis
XP_538880
456
51014
S348
D
K
A
L
G
L
D
S
A
N
E
K
G
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
S348
D
K
A
L
G
L
D
S
A
N
E
K
G
L
Y
Rat
Rattus norvegicus
Q9QVC8
458
51432
S350
N
K
A
L
E
L
D
S
N
N
E
K
G
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
G315
L
A
A
L
G
L
D
G
A
N
E
K
G
L
Y
Chicken
Gallus gallus
NP_001005431
449
50409
Q348
D
K
A
L
G
L
D
Q
D
N
E
K
G
L
Y
Frog
Xenopus laevis
NP_001084593
447
50080
P346
N
K
A
L
E
L
E
P
S
N
E
K
G
L
F
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
P348
N
K
V
M
E
L
D
P
E
N
E
K
A
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
K328
N
E
V
L
A
L
D
K
N
N
V
K
A
L
Y
Honey Bee
Apis mellifera
XP_395748
459
51510
P330
N
E
A
L
K
L
S
P
Q
N
E
K
A
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
A335
A
N
L
N
V
A
M
A
A
I
K
A
E
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
S350
N
K
A
L
E
L
D
S
N
N
E
K
G
L
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
A399
N
T
E
E
K
I
E
A
A
S
K
K
K
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
100
73.3
100
N.A.
100
73.3
N.A.
80
86.6
60
53.3
N.A.
46.6
46.6
N.A.
6.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
86.6
N.A.
80
86.6
86.6
66.6
N.A.
60
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
73.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
74
0
7
7
0
14
47
0
0
7
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
0
0
74
0
7
0
0
0
0
0
0
% D
% Glu:
0
14
7
7
34
0
14
0
7
0
80
0
7
14
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% F
% Gly:
0
0
0
0
40
0
0
7
0
0
0
0
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
67
0
0
14
0
0
7
0
0
14
94
7
0
0
% K
% Leu:
7
0
7
80
0
87
0
0
0
0
0
0
0
87
0
% L
% Met:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
54
7
0
7
0
0
0
0
27
87
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
47
7
7
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
14
0
7
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _