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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
18.18
Human Site:
S445
Identified Species:
28.57
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
S445
T
N
E
K
G
T
D
S
Q
A
M
E
E
E
K
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
S445
T
N
E
K
G
T
D
S
Q
A
M
E
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
T438
S
G
D
H
P
T
D
T
E
M
K
E
E
Q
K
Dog
Lupus familis
XP_538880
456
51014
S445
T
N
E
K
E
A
E
S
Q
A
T
E
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
S444
A
A
G
K
Q
H
E
S
Q
A
M
E
E
G
K
Rat
Rattus norvegicus
Q9QVC8
458
51432
A438
A
G
D
H
P
T
D
A
E
M
K
G
E
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
G406
S
A
C
Q
K
G
E
G
D
E
A
M
D
D
K
Chicken
Gallus gallus
NP_001005431
449
50409
T436
R
V
E
K
E
S
A
T
A
A
C
D
E
G
K
Frog
Xenopus laevis
NP_001084593
447
50080
N437
E
M
K
E
P
D
E
N
G
S
L
K
S
M
A
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
R445
Q
N
K
Q
G
L
K
R
A
R
L
S
Q
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
S419
L
S
K
C
G
E
W
S
E
E
D
A
K
R
E
Honey Bee
Apis mellifera
XP_395748
459
51510
G422
D
V
M
C
G
A
L
G
E
W
G
Q
E
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
K415
K
Q
H
L
E
K
E
K
K
I
Y
G
N
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
A438
A
G
D
H
P
T
D
A
E
M
K
G
E
P
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
N516
A
L
E
I
D
P
N
N
R
E
V
K
L
E
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
100
33.3
60
N.A.
53.3
20
N.A.
6.6
33.3
0
13.3
N.A.
13.3
20
N.A.
0
P-Site Similarity:
100
100
66.6
73.3
N.A.
60
40
N.A.
40
53.3
46.6
46.6
N.A.
46.6
40
N.A.
13.3
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
14
0
0
0
14
7
14
14
34
7
7
0
0
14
% A
% Cys:
0
0
7
14
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
20
0
7
7
34
0
7
0
7
7
7
14
0
% D
% Glu:
7
0
34
7
20
7
34
0
34
20
0
34
60
27
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
20
7
0
34
7
0
14
7
0
7
20
0
14
7
% G
% His:
0
0
7
20
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
0
20
34
7
7
7
7
7
0
20
14
7
7
40
% K
% Leu:
7
7
0
7
0
7
7
0
0
0
14
0
7
0
0
% L
% Met:
0
7
7
0
0
0
0
0
0
20
20
7
0
14
0
% M
% Asn:
0
27
0
0
0
0
7
14
0
0
0
0
7
0
14
% N
% Pro:
0
0
0
0
27
7
0
0
0
0
0
0
0
14
0
% P
% Gln:
7
7
0
14
7
0
0
0
27
0
0
7
7
7
7
% Q
% Arg:
7
0
0
0
0
0
0
7
7
7
0
0
0
7
7
% R
% Ser:
14
7
0
0
0
7
0
34
0
7
0
7
7
0
0
% S
% Thr:
20
0
0
0
0
34
0
14
0
0
7
0
0
0
0
% T
% Val:
0
14
0
0
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _