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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP5 All Species: 39.7
Human Site: S69 Identified Species: 62.38
UniProt: Q13451 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13451 NP_001139247.1 457 51212 S69 S N G K K F D S S H D R N E P
Chimpanzee Pan troglodytes XP_001172411 457 51122 S69 S N G K K F D S S H D R N E P
Rhesus Macaque Macaca mulatta XP_001098079 459 51670 S69 L D G T K F D S S L D R K D K
Dog Lupus familis XP_538880 456 51014 S69 S N G K K F D S S H D R N E P
Cat Felis silvestris
Mouse Mus musculus Q64378 456 50948 S69 S D G K K F D S S H D R K K P
Rat Rattus norvegicus Q9QVC8 458 51432 S69 L D G T K F D S S L D R K D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512517 419 46551 K65 D I G V A T M K K G E I C Q L
Chicken Gallus gallus NP_001005431 449 50409 S69 A N G K K F D S S R D R N E P
Frog Xenopus laevis NP_001084593 447 50080 S65 T D G T K F D S S R D R K D K
Zebra Danio Brachydanio rerio NP_998314 453 51464 S69 L S G K K F D S S L D R K E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 M74 N V I K A F D M G V A T M K L
Honey Bee Apis mellifera XP_395748 459 51510 I73 S V I K A W D I G V A T M K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781282 422 47590 S77 T D G V L F D S S R S R N E K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141458 458 51432 S69 L D G T K F D S S L D R K D K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 S76 L D G T K F D S S R D R A T P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 54 95.1 N.A. 87 53.7 N.A. 69.8 83.1 55.5 58.6 N.A. 39.3 47 N.A. 44.2
Protein Similarity: 100 99.7 73.8 96.7 N.A. 91.6 72.4 N.A. 77.6 88.8 70.9 75.2 N.A. 56.6 61.2 N.A. 62.8
P-Site Identity: 100 100 53.3 100 N.A. 80 53.3 N.A. 6.6 86.6 53.3 73.3 N.A. 20 20 N.A. 53.3
P-Site Similarity: 100 100 66.6 100 N.A. 93.3 66.6 N.A. 20 93.3 73.3 80 N.A. 33.3 33.3 N.A. 66.6
Percent
Protein Identity: N.A. 53.7 N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. 72.4 N.A. 47 N.A. N.A.
P-Site Identity: N.A. 53.3 N.A. 60 N.A. N.A.
P-Site Similarity: N.A. 66.6 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 20 0 0 0 0 0 14 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 47 0 0 0 0 94 0 0 0 74 0 0 27 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 7 0 0 40 0 % E
% Phe: 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 87 0 0 0 0 0 14 7 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 % H
% Ile: 0 7 14 0 0 0 0 7 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 54 74 0 0 7 7 0 0 0 40 20 40 % K
% Leu: 34 0 0 0 7 0 0 0 0 27 0 0 0 0 14 % L
% Met: 0 0 0 0 0 0 7 7 0 0 0 0 14 0 0 % M
% Asn: 7 27 0 0 0 0 0 0 0 0 0 0 34 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 27 0 80 0 0 0 % R
% Ser: 34 7 0 0 0 0 0 80 80 0 7 0 0 0 0 % S
% Thr: 14 0 0 34 0 7 0 0 0 0 0 14 0 7 0 % T
% Val: 0 14 0 14 0 0 0 0 0 14 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _