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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
7.88
Human Site:
T17
Identified Species:
12.38
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
T17
N
E
E
S
P
T
A
T
V
A
E
Q
G
E
D
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
T17
N
G
E
S
P
T
A
T
V
A
E
Q
G
E
D
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
P17
E
S
G
A
Q
S
A
P
L
P
I
E
G
V
D
Dog
Lupus familis
XP_538880
456
51014
A17
S
G
E
N
P
A
A
A
V
A
E
R
G
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
T17
N
G
E
N
P
A
A
T
M
T
E
Q
G
E
D
Rat
Rattus norvegicus
Q9QVC8
458
51432
P17
E
N
G
A
Q
S
A
P
L
P
L
E
G
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
F17
A
Q
K
V
R
G
L
F
R
G
G
S
L
S
D
Chicken
Gallus gallus
NP_001005431
449
50409
A17
E
G
E
V
Q
A
A
A
L
A
E
R
G
E
D
Frog
Xenopus laevis
NP_001084593
447
50080
D17
G
P
E
H
F
T
M
D
G
S
D
I
T
P
K
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
V17
T
N
Q
C
P
T
A
V
F
T
S
R
G
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
E18
G
D
G
G
V
L
K
E
I
L
K
E
G
T
G
Honey Bee
Apis mellifera
XP_395748
459
51510
E17
K
D
G
G
V
M
K
E
I
I
K
E
G
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
P23
E
Y
Q
P
F
P
D
P
L
M
G
T
G
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
P17
E
N
G
A
Q
S
A
P
L
P
L
E
G
V
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
D23
D
D
D
M
D
F
G
D
G
A
S
F
L
K
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
93.3
20
60
N.A.
66.6
20
N.A.
6.6
46.6
13.3
26.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
46.6
80
N.A.
80
46.6
N.A.
20
60
26.6
40
N.A.
33.3
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
20
0
20
60
14
0
34
0
0
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
20
7
0
7
0
7
14
0
0
7
0
0
0
67
% D
% Glu:
34
7
40
0
0
0
0
14
0
0
34
34
0
34
0
% E
% Phe:
0
0
0
0
14
7
0
7
7
0
0
7
0
0
0
% F
% Gly:
14
27
34
14
0
7
7
0
14
7
14
0
80
0
14
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
14
7
7
7
0
7
0
% I
% Lys:
7
0
7
0
0
0
14
0
0
0
14
0
0
7
7
% K
% Leu:
0
0
0
0
0
7
7
0
34
7
14
0
14
0
0
% L
% Met:
0
0
0
7
0
7
7
0
7
7
0
0
0
0
0
% M
% Asn:
20
20
0
14
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
7
34
7
0
27
0
20
0
0
0
7
0
% P
% Gln:
0
7
14
0
27
0
0
0
0
0
0
20
0
7
0
% Q
% Arg:
0
0
0
0
7
0
0
0
7
0
0
20
0
0
0
% R
% Ser:
7
7
0
14
0
20
0
0
0
7
14
7
0
7
0
% S
% Thr:
7
0
0
0
0
27
0
20
0
14
0
7
7
14
0
% T
% Val:
0
0
0
14
14
0
0
7
20
0
0
0
0
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _