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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
14.85
Human Site:
T433
Identified Species:
23.33
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
T433
N
K
A
M
G
K
K
T
S
E
G
V
T
N
E
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
T433
N
K
A
M
G
K
K
T
S
E
G
V
T
N
E
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
K426
A
E
E
E
N
K
A
K
A
E
A
S
S
G
D
Dog
Lupus familis
XP_538880
456
51014
T433
S
K
A
M
G
K
K
T
L
E
G
V
T
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
K432
A
S
K
A
G
S
K
K
A
V
E
G
A
A
G
Rat
Rattus norvegicus
Q9QVC8
458
51432
K426
A
E
E
E
H
K
A
K
T
E
V
A
A
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
S394
D
A
K
V
E
E
A
S
N
L
R
D
S
A
C
Chicken
Gallus gallus
NP_001005431
449
50409
A424
A
E
R
D
A
K
E
A
A
S
K
T
R
V
E
Frog
Xenopus laevis
NP_001084593
447
50080
T425
E
S
T
E
V
P
P
T
P
S
D
I
E
M
K
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
S433
L
K
R
K
K
E
E
S
V
I
S
D
Q
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
R407
D
K
E
T
E
P
P
R
E
T
D
V
L
S
K
Honey Bee
Apis mellifera
XP_395748
459
51510
L410
K
Q
K
E
E
E
K
L
R
E
Q
P
D
V
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
S403
A
K
N
Q
L
T
L
S
N
Q
K
L
K
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
K426
A
E
E
E
H
K
A
K
T
E
V
A
A
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
F504
S
D
L
D
L
A
E
F
D
V
K
K
A
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
100
13.3
86.6
N.A.
13.3
13.3
N.A.
0
13.3
6.6
13.3
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
40
93.3
N.A.
20
33.3
N.A.
40
33.3
20
40
N.A.
33.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
7
20
7
7
7
27
7
20
0
7
14
27
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
14
7
0
14
0
0
0
0
7
0
14
14
7
0
20
% D
% Glu:
7
27
27
34
20
20
20
0
7
47
7
0
7
0
34
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
27
0
0
0
0
0
20
7
0
20
7
% G
% His:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% I
% Lys:
7
40
20
7
7
47
34
27
0
0
20
7
7
0
20
% K
% Leu:
7
0
7
0
14
0
7
7
7
7
0
7
7
7
0
% L
% Met:
0
0
0
20
0
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
14
0
7
0
7
0
0
0
14
0
0
0
0
27
0
% N
% Pro:
0
0
0
0
0
14
14
0
7
0
0
7
0
0
0
% P
% Gln:
0
7
0
7
0
0
0
0
0
7
7
0
7
7
0
% Q
% Arg:
0
0
14
0
0
0
0
7
7
0
7
0
7
0
0
% R
% Ser:
14
14
0
0
0
7
0
20
14
14
7
7
14
7
0
% S
% Thr:
0
0
7
7
0
7
0
27
14
7
0
7
20
0
0
% T
% Val:
0
0
0
7
7
0
0
0
7
14
14
27
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _