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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP5 All Species: 42.12
Human Site: Y111 Identified Species: 66.19
UniProt: Q13451 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13451 NP_001139247.1 457 51212 Y111 H L L C K P E Y A Y G S A G S
Chimpanzee Pan troglodytes XP_001172411 457 51122 Y111 H L L C K P E Y A Y G S A G S
Rhesus Macaque Macaca mulatta XP_001098079 459 51670 Y111 H I T C K P E Y A Y G S A G S
Dog Lupus familis XP_538880 456 51014 Y111 H L L C K P E Y A Y G S A G S
Cat Felis silvestris
Mouse Mus musculus Q64378 456 50948 Y111 H L L C K P E Y A Y G S A G H
Rat Rattus norvegicus Q9QVC8 458 51432 Y111 H I T C K P E Y A Y G S A G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512517 419 46551 E107 E L L D F K G E D L F E D G G
Chicken Gallus gallus NP_001005431 449 50409 Y111 Y L L C K P E Y A Y G A A G S
Frog Xenopus laevis NP_001084593 447 50080 Y107 Q I I C K P E Y A Y G T S G S
Zebra Danio Brachydanio rerio NP_998314 453 51464 Y111 L M L C K P E Y A Y G S A G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 M116 T L I F E L E M L G W K G E D
Honey Bee Apis mellifera XP_395748 459 51510 M115 T L K F E I E M I S W K G E D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781282 422 47590 Y119 V I T C K P E Y A Y G K S S K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141458 458 51432 Y111 H I T C K P E Y A Y G S A G S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 L118 V F T I P A E L A Y G E S G S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 54 95.1 N.A. 87 53.7 N.A. 69.8 83.1 55.5 58.6 N.A. 39.3 47 N.A. 44.2
Protein Similarity: 100 99.7 73.8 96.7 N.A. 91.6 72.4 N.A. 77.6 88.8 70.9 75.2 N.A. 56.6 61.2 N.A. 62.8
P-Site Identity: 100 100 86.6 100 N.A. 93.3 86.6 N.A. 20 86.6 66.6 86.6 N.A. 13.3 13.3 N.A. 53.3
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 20 100 93.3 93.3 N.A. 26.6 20 N.A. 66.6
Percent
Protein Identity: N.A. 53.7 N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. 72.4 N.A. 47 N.A. N.A.
P-Site Identity: N.A. 86.6 N.A. 40 N.A. N.A.
P-Site Similarity: N.A. 93.3 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 80 0 0 7 60 0 0 % A
% Cys: 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 0 0 7 0 0 0 7 0 14 % D
% Glu: 7 0 0 0 14 0 94 7 0 0 0 14 0 14 0 % E
% Phe: 0 7 0 14 7 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 7 80 0 14 80 7 % G
% His: 47 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 34 14 7 0 7 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 74 7 0 0 0 0 0 20 0 0 7 % K
% Leu: 7 54 47 0 0 7 0 7 7 7 0 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 14 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 74 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 7 0 54 20 7 67 % S
% Thr: 14 0 34 0 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 74 0 80 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _