KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP5
All Species:
38.18
Human Site:
Y159
Identified Species:
60
UniProt:
Q13451
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13451
NP_001139247.1
457
51212
Y159
T
K
R
K
G
E
G
Y
S
N
P
N
E
G
A
Chimpanzee
Pan troglodytes
XP_001172411
457
51122
Y159
T
K
R
K
G
E
G
Y
S
N
P
N
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
Y161
I
R
T
R
G
E
G
Y
A
K
P
N
E
G
A
Dog
Lupus familis
XP_538880
456
51014
Y159
I
K
Q
K
G
E
G
Y
S
N
P
N
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64378
456
50948
Y159
I
K
R
K
G
E
G
Y
S
N
P
N
E
G
A
Rat
Rattus norvegicus
Q9QVC8
458
51432
Y161
I
R
T
R
G
E
G
Y
A
R
P
N
D
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
G145
H
L
E
G
C
C
S
G
R
T
F
D
C
R
D
Chicken
Gallus gallus
NP_001005431
449
50409
Y159
I
K
R
K
G
E
G
Y
S
N
P
N
E
G
A
Frog
Xenopus laevis
NP_001084593
447
50080
Y157
I
R
V
K
G
E
G
Y
S
K
P
N
E
G
A
Zebra Danio
Brachydanio rerio
NP_998314
453
51464
Y159
I
K
V
K
G
E
G
Y
S
N
P
N
E
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
H155
D
G
A
F
V
K
A
H
I
S
G
S
F
E
G
Honey Bee
Apis mellifera
XP_395748
459
51510
N160
V
H
L
M
G
M
Y
N
G
K
I
F
E
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
Y168
I
V
T
E
G
Q
E
Y
D
T
P
N
D
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
Y161
I
R
T
R
G
E
G
Y
A
R
P
N
D
G
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
W167
I
L
A
V
G
E
K
W
E
N
P
K
D
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
54
95.1
N.A.
87
53.7
N.A.
69.8
83.1
55.5
58.6
N.A.
39.3
47
N.A.
44.2
Protein Similarity:
100
99.7
73.8
96.7
N.A.
91.6
72.4
N.A.
77.6
88.8
70.9
75.2
N.A.
56.6
61.2
N.A.
62.8
P-Site Identity:
100
100
60
86.6
N.A.
93.3
53.3
N.A.
0
93.3
73.3
86.6
N.A.
0
13.3
N.A.
33.3
P-Site Similarity:
100
100
80
93.3
N.A.
93.3
80
N.A.
6.6
93.3
80
86.6
N.A.
26.6
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
53.7
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
72.4
N.A.
47
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
80
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
0
7
0
20
0
0
0
0
0
74
% A
% Cys:
0
0
0
0
7
7
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
7
0
0
7
27
7
14
% D
% Glu:
0
0
7
7
0
74
7
0
7
0
0
0
60
14
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
7
7
7
0
0
% F
% Gly:
0
7
0
7
87
0
67
7
7
0
7
0
0
67
7
% G
% His:
7
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
67
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% I
% Lys:
0
40
0
47
0
7
7
0
0
20
0
7
0
0
0
% K
% Leu:
0
14
7
0
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
47
0
74
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
27
27
20
0
0
0
0
7
14
0
0
0
7
7
% R
% Ser:
0
0
0
0
0
0
7
0
47
7
0
7
0
0
0
% S
% Thr:
14
0
27
0
0
0
0
0
0
14
0
0
0
0
0
% T
% Val:
7
7
14
7
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _